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MetabolomicsQuantitative metabolomics of plasma and tissue interstitial fluids from mice

This study presents quantitative metabolomic measurements of plasma and tissue interstitial fluids (IF) collected from healthy C57BL/6J mice. Using liquid chromatography–mass spectrometry (LC–MS) and external chemical standards, absolute concentrations were determined for over one hundred polar m...

2025-12-30 | MTBLS13165 | MetaboLights
MetabolomicsUntargeted Metabolomics of the enthesis interstitial fluid of wild-type and Nlrp3-/- mice with sham operation and injury post 7 days
In order to investigate the effect of the NLRP3 inflammasome on the regeneration of enthesis, we established an enthesis injury and repair model in wild-type and NLRP3-/- mice. The interstitial fluid of enthesis was extracted, and untargeted metabolomics was conducted to discover differential metabo...
2025-07-08 | MTBLS12150 | MetaboLights
MetabolomicsTime-dependent stability of plasma and liver interstitial fluid metabolites during sample handling in mice

This study assesses the stability of metabolite levels in plasma and liver interstitial fluid (IF) from mice subjected to different handling times prior to extraction. Blood and tissues from female C57BL/6J mice were collected and either processed immediately or held on ice for 5, 10, or 30 minut...

2025-12-30 | MTBLS13164 | MetaboLights
MetabolomicsMulti-omics analysis identifies a microbiota–bile acid–TLR signaling axis driving bladder injury in interstitial cystitis

Hunner-type interstitial cystitis/bladder pain syndrome (HIC) is a complex and clinically challenging chronic disorder characterized by bladder-centered symptoms, including persistent pelvic pain and urinary urgency frequency, with elusive pathogenesis involving poorly defined multi-system intera...

2025-12-16 | MTBLS13513 | MetaboLights
MetabolomicsMulti-omics analysis identifies a microbiota–bile acid–TLR signaling axis driving bladder injury in interstitial cystitis

Hunner-type interstitial cystitis/bladder pain syndrome (HIC) is a complex and clinically challenging chronic disorder characterized by bladder-centered symptoms, including persistent pelvic pain and urinary urgency frequency, with elusive pathogenesis involving poorly defined mult...

2025-12-16 | MTBLS13512 | MetaboLights
MetabolomicsMetabolic profiling of mouse tissues and tissue interstitial fluids
Not available
ORGANISM(S): Mus musculus 
ST002223 | MetabolomicsWorkbench
MetabolomicsIdentification of urine metabolites in patients with interstitial cystitis using untargeted metabolomics (part II)
Not available
ORGANISM(S): Homo sapiens 
ST001122 | MetabolomicsWorkbench
MetabolomicsIdentification of urine metabolites in patients with interstitial cystitis using untargeted metabolomics (part I)
Not available
ORGANISM(S): Homo sapiens 
ST001121 | MetabolomicsWorkbench
MetabolomicsUrinary Volatile Compound, Associated with Chronic Inflammation In Interstitial Cystitis
Not available
ORGANISM(S): Homo sapiens 
ST000603 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling by array of human female interstitial cystitis urothelial cells after inducing differentiation
Purpose: Evaluate gene expression profiles after inducing differentiation in cultured interstitial cystitis (IC) and control urothelial cells. Materials and Methods: Bladder biopsies were taken from IC patients and controls (women having surgery for stress incontinence). Primary cultures were gro...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11839 | biostudies-arrayexpress
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