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ProteomicsSWATH DIA MS data of human plasma from donors with intervertebral disc degeneration
SWATH DIA mass spectometry was peformed on plasma samples from donors with mild or severe intervetebral disc degeneration to identify biomarkers associated with degeneration progression.
ORGANISM(S): Homo sapiens (Human) 
2025-02-14 | PXD055158 | Pride
Human Plasma Ivd Intervetebral Disc degeneration 
ProteomicsWhole-protein lactylation proteome analysis of rat nucleus pulposus tissues
Lactate accumulation is a hallmark and contributing factor of intervertebral disc degeneration (IVDD). Lactate accumulation facilitates protein lactylation, while the role and mechanism of protein lactylation in IVDD remain unclear. In this study, we performed sequencing of the lactylation sites of ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-13 | PXD072520 | Pride
Intervetebral disc degeneration lactylation sod1 
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