Sort   by:  
 Page size 
MetabolomicsThe Green Tea Modulates Large Intestinal Microbiome and Exo/Endogenous Metabolome altered through Chronic UVB-exposure (Endogenous assays)
The attenuating effects of green tea supplements (GTS) against the ultraviolet (UV) radiation induced skin damages are distinguished. However, the concomitant effects of GTS on the large intestinal microbiomes and associated metabolomes are largely unclear. Herein, we performed an integrated microbi...
2018-09-14 | MTBLS527 | MetaboLights
MetabolomicsContribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice
The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fun...
2022-01-14 | MTBLS1679 | MetaboLights
MetabolomicsAppropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
16S metagenomic analysis has provided much information about the intestinal microbiome. However, there are no reports that describe their appropriate taxonomic classification rank. Moreover, studies differ on the taxonomic ranking of the same microorganism. Intestinal microbiome exerts a significant...
2017-02-20 | MTBLS376 | MetaboLights
MetabolomicsAntibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function
Antibiotics revolutionized medicine, however, it is now clear that broad-spectrum antibiotics alter the composition and function of the host’s microbiome. The microbiome plays a key role in human health and its perturbation is increasingly recognized as contributing to many human diseases. Wide spre...
2021-01-11 | MTBLS1257 | MetaboLights
MetabolomicsDiallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
Diallyl disulfide (DADS), a garlic extract also known as allicin, has been reported to have numerous biological activities, including anticancer, antifungal, and inflammation-inhibiting activities, among others. Although many studies have assessed whether DADS can treat Candida albicans infec...
2022-05-03 | MTBLS3750 | MetaboLights
MetabolomicsMapping human microbiome drug metabolism by gut bacteria and their genes

Individuals vary widely in their drug responses, which can be dangerous and expensive due to treatment delays and adverse effects. Growing evidence implicates the gut microbiome in this variability, however the molecular mechanisms remain largely unknown. We measured the ability of 76 diverse hum...

2019-07-10 | MTBLS896 | MetaboLights
MetabolomicsUntargeted metabolomics analysis of intestinal contents in Common Carp

To elucidate the metabolic mechanisms underlying the beneficial effects of Enterococcus faecalis on host health under high-carbohydrate-high-fat (HCHF) stress, we performed an untargeted metabolomics analysis on intestinal contents of common carp (Cyprinus carpio). Fish were fed an HCHF diet with...

2026-08-09 | MTBLS15296 | MetaboLights
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
MetabolomicsA study of the relationship between post-cholecystectomy diarrhea and intestinal microecology

Background and Aims:Cholecystectomy is the preferred surgical procedure for treating gallstones,but the incidence of postcholecystectomy diarrhea (PCD) varies considerably,and its association with the intestinal microbiota remains unclear.This study aims to investigate the effects of cholecystect...

2025-12-19 | MTBLS13528 | MetaboLights
MetabolomicsGut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease
Not available
ORGANISM(S): Mus musculus 
ST000338 | MetabolomicsWorkbench
Sort   by:  
 Page size