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MetabolomicsMultiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level (Metabolite profiling)

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically very heterogenous. The application of omics technologies - mainly studying nucleic acids - has significantly improved MB classification and stratification, but treatment options are still unsatisfactor...

2024-05-30 | MTBLS9830 | MetaboLights
MetabolomicsProteome allocations change linearly with the specific growth rate of Saccharomyces cerevisiae under glucose limitation

Saccharomyces cerevisiae is a widely used cell factory; therefore, it is important to understand how it organizes key functional parts when cultured under different conditions. Here, we perform a multiomics analysis of S. cerevisiae by culturing the strain with a wide range of s...

2022-08-31 | MTBLS697 | MetaboLights
MetabolomicsTen Mouse Organs Proteome and Metabolome Atlas from Adult to Aging

The complexity of the aging process, encompassing numerous organs and systems, poses a significant challenge in identifying and targeting key factors that drive age-related decline. The multi-organ synchronous molecular intricacies underlying natural aging remain elusive. Here we presented a data...

2025-08-29 | MTBLS10642 | MetaboLights
UnknownA Cross-Linking-Aided Immunoprecipitation/Mass Spectrometry Workflow Reveals Extensive Intracellular Trafficking in Time-Resolved, Signal-Dependent Epidermal Growth Factor Receptor Proteome.
Not available
S-EPMC7532284 | biostudies-literature
UnknownAcetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk.
Not available
S-EPMC6718414 | biostudies-literature
UnknownTransgenic, fluorescent Leishmania mexicana allow direct analysis of the proteome of intracellular amastigotes.
Not available
S-EPMC2556020 | biostudies-literature
ProteomicsExtra and quantitatve intracellular proteomics for Streptomyces sp. SirexAA-E
In this study, we performed an extracellular proteomics and pair-wise TMT-labeling quantitative intracellular proteomics of SirexAA-E grown on glucose, xylose, xylobiose, or xylan-containing medium to gain a knowledge of extracellular and intracellular xylan responses of this bacterium. Moreover, th...
ORGANISM(S): Streptomyces sp. SirexAA-E 
2025-11-11 | PXD067972 | Pride
Tmt Streptomyces sp. sirexaa-e 
UnknownAbsolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Not available
S-EPMC4125727 | biostudies-literature
ProteomicsProteomics of Intracellular Freezing Survival
Panagrolaimus sp. DAW1, a nematode cultured from the Antarctic, has the extraordinary physiological ability to survive total intracellular freezing throughout all of its compartments. While a few other organisms, all nematodes, have subsequently also been found to survive freezing in this manner, P....
ORGANISM(S): Panagrolaimus 
2020-05-01 | PXD018121 | Pride
Intracellular freezing Nematode Panagrolaimus Cryoprotection 
ProteomicsIntracellular proteome response of the gut bacterium Bacteroides thetaiotaomicron to the metabolic switch from glucose to sucrose as the sole carbon source
Bacteroides thetaiotaomicron (B. thetaiotaomicron) is an essential bacterial representative of the human gut microbiome that metabolizes a wide range of dietary and mucosal polysaccharides. Here, we analyze the intracellular proteomic response of in vitro grown B. thetaiotaomicron to the metabolic s...
ORGANISM(S): Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) 
2022-10-15 | PXD033704 | Pride
Label free quantifications Isobaric labeling Ibd Inflammation Tmt Carbohydrate metabolism Bottom up Lfq Bacterial proteomics High/low ph 2d-lc 
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