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MetabolomicsSalmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
GenomicsGenomes from the Network Collection of Symbiont Microorganisms and Their Consortia (NCSM) of the Institute for Cellular and Intracellular Symbiosis of the Ural Branch of the Russian Academy of Sciences, Orenburg, Russia
Genomes from the Network Collection of Symbiont Microorganisms and Their Consortia (NCSM) of the Institute for Cellular and Intracellular Symbiosis of the Ural Branch of the Russian Academy of Sciences, Orenburg, Russia Genome sequencing and assembly
PRJNA1231275 | ENA
ProteomicsSymbiosis induces widespread changes in the proteome of the model cnidarian Aiptasia
Coral reef ecosystems are metabolically founded on the mutualism between corals and photosynthetic dinoflagellates of the genus Symbiodinium. The glass anemone Aiptasia sp. has become a tractable model for this symbiosis. We utilized label-free liquid chromatography electrospray-ionization tandem ma...
ORGANISM(S): Aiptasia pulchella (Tropical sea anemone) 
2017-02-22 | PXD003202 | Pride
Model organism Coral Symbiosis Cnidarian Label-free Aiptasia 
ProteomicsThe Trichoplax H2 holobiont: a simple animal and its two intracellular symbionts
The Placozoa are an enigmatic group of simple marine metazoans where all taxa harbor intracellular bacteria. Despite four decades of research, the bacterial identities, their location and their roles remain elusive. Here we show that the placozoan Trichoplax H2 is associated with two intracellular b...
ORGANISM(S): Trichoplax sp. H2 Candidatus Midichloriaceae Candidatus Margulisbacteria 
2019-04-18 | PXD012106 | Pride
Grellia incantans Rough endoplasmic reticulum Trichoplax h2 Ruthmannia eludens Placozoa Intracellular symbiosis Midichloriaceae Rickettsiales Margulisbacteria 
UnknownGenome reduction and horizontal gene transfer in the evolution of Endomicrobia-rise and fall of an intracellular symbiosis with termite gut flagellates.
Not available
S-EPMC11257099 | biostudies-literature
TranscriptomicsComparison of gene expression in 23 Cryptococcus gattii isolates
An array analysis of C. gattii (C. bacillosporus), intended to identify loci associated with the hypervirulence of the Vancouver Island Outbreak (VIO). 23 C. gattii isolates, representing both VIO strains and control strains, were grown for 24 hours in mammalian macrophages. RNA was isolated and g...
ORGANISM(S): Cryptococcus bacillisporus 
2010-05-15 | E-GEOD-17052 | biostudies-arrayexpress
UnknownDistinct ankyrin repeat subdomains control VAPYRIN locations and intracellular accommodation functions during arbuscular mycorrhizal symbiosis.
Not available
S-EPMC9445082 | biostudies-literature
UnknownmTORC1 regulates phagosome digestion of symbiotic bacteria for intracellular nutritional symbiosis in a deep-sea mussel.
Not available
S-EPMC10446485 | biostudies-literature
GenomicsSpatiotemporal regulation of arbuscular mycorrhizal symbiosis at cellular resolution [MC]
Spatiotemporal regulation of arbuscular mycorrhizal symbiosis at cellular resolution [MC]
PRJNA1401832 | ENA
TranscriptomicsTranscriptional responses to arbuscular mycorrhizal symbiosis development are conserved in the liverwort Marchantia paleacea
The mutualistic arbuscular mycorrhizal (AM) symbiosis arose in land plants more than 450 million years ago. This symbiosis is still widely found across major land plant lineages, including bryophytes. Despite its broad taxonomic distribution, little is known about the molecular components underpinni...
ORGANISM(S): Marchantia paleacea 
2024-08-08 | GSE245702 | GEO
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