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MetabolomicsIon mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
Aberrant sterol lipid metabolism is associated with physiological dysfunctions in the aging brain and aging-dependent disorders such as neurodegenerative diseases. There is an unmet demand to comprehensively profile sterol lipids spatially and temporally in different brain regions during aging. Here...
2021-05-24 | MTBLS2457 | MetaboLights
MetabolomicsA Novel Approach to Characterize the Lipidome of Marine Archaeon Nitrosopumilus maritimus by Ion Mobility Mass Spectrometry

Archaea are differentiated from the other two domains of life by their biomolecular characteristics. One such characteristic is the unique structure and composition of their lipids. Characterization of the whole set of lipids in a biological system (the lipidome) remains technologically challengi...

2021-12-16 | MTBLS3714 | MetaboLights
MetabolomicsUnknown Metabolite Annotation in Mouse Aging using Ion Mobility Collision Cross-Section Atlas (AllCCS)

The metabolome includes not just known but also unknown metabolites; however, metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility – mass spectrometry (IM-MS) has emerged as a promising technology by providing multi-dimensional characterizations of metabolites. He...

2020-07-28 | MTBLS1622 | MetaboLights
MetabolomicsKnown Metabolite Annotation in Different Biological Samples using Ion Mobility Collision Cross-Section Atlas (AllCCS)

The metabolome includes not just known but also unknown metabolites; however, metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility – mass spectrometry (IM-MS) has emerged as a promising technology by providing multi-dimensional characterizations of metabolites. He...

2020-07-28 | MTBLS1693 | MetaboLights
ProteomicsComplement Reporter Ion Quantification with a Quadrupole-Ion Trap Instrument
Proteomics workflows have traditionally been divided into discovery-based and targeted approaches, with instrumentation optimized for each. Discovery experiments typically utilize high-resolution analyzers such as the Orbitrap™, while targeted workflows rely on the sensitivity and specificity of tri...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) Xenopus laevis (African clawed frog) 
2025-09-08 | PXD062540 | Pride
Stellar Complement reporter ion Quadrupole-ion trap Multiplexed shotgun proteomics 
ProteomicsEvaluating linear ion trap incorporation for MS3-based multiplexed single-cell proteomics
The project aims to evaluate the use of a linear ion trap to increase the sensitivity of multiplexed single-cell proteomics. Using diluted mouse peptide samples from C10 and Raw, we compared the proteome coverages, data missingness, and quantification performance between linear ion trap and Orbitrap...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-08-22 | MSV000090178 | MassIVE
TranscriptomicsNovel primate miRNAs co-evolved with ancient target genes in germinal zone specific expression patterns [RISC trap immunoprecipitation]
Major non primate-primate differences in corticogenesis include the dimensions, precursor lineages and developmental timing of the germinal zones (GZ). microRNAs (miRNAs) of laser dissected GZ compartments and cortical plate (CP) from embryonic E80 macaque visual cortex were deep sequenced. The CP a...
ORGANISM(S): Homo sapiens 
2014-02-27 | E-GEOD-52607 | biostudies-arrayexpress
ProteomicsAnalysis of Human Plasma by LC-MSMS and Orbital Ion Trap
Identification of human plasma by LC-MSMS with orbital ion trap after collection over quaternary amine resin and digestion with trypsin.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055594 | Pride
Lc-msms Random and independent sampling Human plasma Orbital ion trap Quaternary amine Partition chromatography 
ProteomicsAnalysis of Human Plasma by LC-MSMS and Linear Ion Trap
Identification of proteins from normal human plasma by LC-MSMS with linear ion trap after collection over quaternary amine resin and digestion with trypsin.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055704 | Pride
Lc-msms Random and independent sampling Human plasma Quaternary amine Linearl ion trap Partition chromatography 
TranscriptomicsTrap-80-dependence of TNF-alpha-induced genes
In fibroblasts, p65-dependent genes can be sub-divided, depending on whether they are Trap-80-dependent or -independent. To examine the generality of this grouping, we performed a microarray analysis of wild-type and Trap-80 knock-down fibroblasts, before and after stimulation of NF-kappaB activity...
ORGANISM(S): Mus musculus 
2010-04-09 | E-GEOD-12697 | biostudies-arrayexpress
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