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ProteomicsNuclear activities and interactome of the NS5 protein of Tick-Borne Encephalitis Virus
Orthoflaviviruses are RNA viruses responsible for significant diseases in humans, domesticated animals and wildlife. Their NS5 protein is central in viral replication, functioning both as an RNA-dependent RNA polymerase and a methyltransferase, while also modulating cellular processes, including the...
ORGANISM(S): Homo sapiens (Human) 
2026-07-28 | PXD080823 | Pride
Tbev Ip-ms Ns5 
ProteomicsCoronavirus protein interaction mapping in bat and human cells identifies molecular and genetic switches for immune evasion and replication
Coronaviruses, including SARS-CoV-2, can cause severe disease in humans, whereas reservoir hosts like Rhinolophus bats appear to remain asymptomatic for reasons that are not well-recognized. To understand how host-specific protein-protein interactions (PPIs) shape infection outcomes, we generated co...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens (Human) Bat coronavirus RaTG13 Severe acute respiratory syndrome coronavirus 2 
2026-06-29 | PXD065873 | Pride
Host-pathogen interactions Ratg13 Sars-cov-2 Apms Bats 
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