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ProteomicsProteomic profiling of Ips typographus adult male protein extracts
Mass spectrometry-based proteomic profiling of Ips typographus adult male protein extracts prepared using NP-40 and CHAPS extraction buffers. The dataset supports the characterization of beetle-derived protein elicitors used to study induced defense responses in Norway spruce (Picea abies) seedlings...
ORGANISM(S): Ips typographus 
2026-09-28 | PXD078890 | Pride
Ips typographus Lcms Norway spruce 
TranscriptomicsIncomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
Human induced pluripotent stem (iPS) cells are remarkably similar to embryonic stem (ES) cells, but recent reports indicate that there may be important differences between them. We carried out a systematic comparison of human iPS cells generated from hepatocytes (representative of endoderm), skin fi...
ORGANISM(S): Homo sapiens 
2011-04-17 | E-GEOD-23034 | biostudies-arrayexpress
TranscriptomicsHuman iPS cells and fibroblasts
This SuperSeries is composed of the following subset Series: GSE18226: Expression data from human iPS cells and fibroblasts GSE18227: DNA methylation data from human iPS cells and fibroblasts Refer to individual Series
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18111 | biostudies-arrayexpress
TranscriptomicsExpression data from human iPS cells and fibroblasts
DNA methylation is often inversely correlated with gene expression. We used expression microarrays to determine the relationship between DNA methylation and gene expression in 6 iPS cell lines and the fibroblasts from which they were derived. We isolated RNA from iPS cells and fibroblasts for which ...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18226 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse induced pluripotent stem cells
We have previously shown that pluripotent stem cells are induced from mouse fibroblasts by retroviral introduction of Oct3/4, Sox2, c-Myc and Klf4, and subsequent selection for Fbx15 expression. These iPS (induced pluripotent stem) cells are similar to embryonic stem (ES) cells in morphology, prolif...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7841 | biostudies-arrayexpress
TranscriptomicsDNA methylation data from human iPS cells and fibroblasts
DNA methylation is often inversely correlated with gene expression. We used custom Nimblegen microarrays to determine the relationship between DNA methylation and gene expression in 6 iPS cell lines and the fibroblasts from which they were derived. We isolated genomic DNA from iPS cells and fibrobla...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18227 | biostudies-arrayexpress
TranscriptomicsUniform, integration-free iPS cells with a safeguard system using human artificial chromosome vectors
Human artificial chromosomes (HACs) have unique characteristics as gene-delivery vector, e.g., episomal transmission and transfer of multiple, large transgenes. Here, we demonstrate the advantages of HAC vectors for reprogramming mouse embryonic fibroblasts (MEFs) to induced pluripotent stem (iPS) c...
ORGANISM(S): Mus musculus 
2011-10-15 | E-GEOD-29441 | biostudies-arrayexpress
TranscriptomicsCell Fusion Enhances Mesendodermal Differentiation of Human Induced Pluripotent Stem Cells.
Human induced pluripotent stem cells (iPS cells) resemble embryonic stem cells and can differentiate into cell derivatives of all three germ layers. However, frequently the differentiation efficiency of iPS cells into some lineages is rather poor. Here, we found that fusion of iPS cells with human h...
ORGANISM(S): Homo sapiens 
2014-08-06 | E-GEOD-58457 | biostudies-arrayexpress
TranscriptomicsComparisons between fully and partially reprogrammed iPS cells induced by pMX-Klf4, pMX-Oct4 and pMX-Sox2 retroviruses
Induced pluripotent stem (iPS) cell reprogramming is a gradual epigenetic process that reactivates the pluripotent transcriptional network by erasing and establishing heterochromatin marks. Here, we characterize the physical structure of heterochromatin domains in full and partial mouse iPS cells b...
ORGANISM(S): Mus musculus 
2011-09-21 | E-GEOD-21595 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse ES and iPS cells
Induced pluripotent stem (iPS) cells were produced from reprogramming of somatic cells, and they are shown to possess pluripotent properties similar to embryonic stem (ES) cells. Here we used microarrays to detail the global expression pattern among the ES cells and iPS cells, as well as the origina...
ORGANISM(S): Mus musculus 
2010-05-28 | E-GEOD-21515 | biostudies-arrayexpress
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