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MetabolomicsToxoplasma gondii metabolic flexibility in response to iron deprivation

Iron is an essential nutrient for many critical cellular processes. As a consequence of diverse and dynamic host environments, the obligate intracellular parasite Toxoplasma gondii must adapt to iron limited conditions. To investigate the adaptations critical to parasite survival under these cond...

2026-03-18 | MTBLS12831 | MetaboLights
TranscriptomicsTranscription profiling of rat duodenal samples at different developmental stages and the effects of iron-deficiency
The effect of iron-deficiency on duodenal gene expression was investigated in rats at different developmental stages.
ORGANISM(S): Rattus norvegicus 
2007-09-15 | E-GEOD-1892 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CaCo-2 cells following various iron treatments
We investigated transcriptional response of CaCo-2 cells to iron treatments, we studied hemin effect by adding hemin to DMEM-FBS medium and iron deficiency effects in using an iron free medium compared to the same supplemented with FAC (ferric ammonium citrate). Experiment Overall Design: Biologica...
ORGANISM(S): Homo sapiens 
2008-01-19 | E-GEOD-3573 | biostudies-arrayexpress
TranscriptomicsIron (Fe) deficiency in Citrus
Transcription profiling of citrus rootstock Poncirus trifoliata (L.) Raf. Keywords: Abiotic stress (Iron chlorosis) Total RNA from four replicates for each sample category (Poncirus trifoliata (L.) Raf watered for 60 days with 18 uM Fe-EDDHA or without Fe-EDDHA) were generated and compared.
ORGANISM(S): Poncirus trifoliata 
2010-05-19 | E-GEOD-17255 | biostudies-arrayexpress
Proteomics,MultiomicsTranscriptional and translational regulatory responses to iron limitation in the globally distributed marine bacterium Candidatus Pelagibacter ubique
Investigation of the gene expression responses of Candidatus Pelagibacter ubique cultures to iron limitation in natural seawater media supplemented with a siderophore to chelate iron. Quantitative peptide mass spectrometry revealed that sfuC protein abundance increased 27-fold, despite an average de...
ORGANISM(S): Candidatus Pelagibacter Ubique (ncbitaxon:198252) 
2020-05-18 | MSV000085445 | MassIVE
ProteomicsMechanisms and Novel Proteins for Iron Oxide Mineral Reduction in the Hyperthermophilic Crenarchaeon Pyrodictium delaneyi
Dissimilatory iron reduction by hyperthermophilic archaea occurs in many geothermal environments and generally relies on microbe-mineral interactions that transform various iron oxide minerals. In this study, the physiology of dissimilatory iron and nitrate reduction was examined in the hyperthermop...
ORGANISM(S): Pyrodictium delaneyi 
2020-12-23 | PXD020757 | Pride
Tmt  hyperthermophile  archaea  iron reducer 
TranscriptomicsMR-1 gene expression profiles of iron response
Time-series transcriptional profiles of Shewanella oneidensis type strain MR-1 under iron depletion and repletion conditions. Iron homeostasis of Shewanella oneidensis, a gamma-proteobacterium possessing high iron content, is regulated by a global transcription factor Fur. However, knowledge is inco...
ORGANISM(S): Shewanella oneidensis MR-1 
2010-01-12 | E-GEOD-15334 | biostudies-arrayexpress
TranscriptomicsDifferential expression of genes in the WT and hupB KO strain of Mycobacterium tuberculosis H37Rv upon iron limitation
HupB is a 28 kDa in Mycobacterium tuberculosis that is co-expressed with the siderophores mycobactin and carboxymycobactin upon iron limitation. High levels of all the three components are seen in low iron (LI; 0.02 M-BM-5g Fe / mL) organisms, with negligible expression in high iron organisms (HI; 8...
ORGANISM(S): Mycobacterium tuberculosis 
2014-03-18 | E-GEOD-53254 | biostudies-arrayexpress
TranscriptomicsTranscriptional characterization of tomato roots response to iron deficiency
Iron (Fe) deficiency is a yield-limiting factor for a variety of field crops across the world and generally results from the interaction of limited soil Fe bioavailability and susceptible genotype cultivation. Tomato, a Strategy I, model plant for Fe deficiency, is an important economical crop. Toma...
ORGANISM(S): Solanum lycopersicum 
2012-03-22 | E-GEOD-31112 | biostudies-arrayexpress
TranscriptomicsM. sedula transcriptional response to ferrous iron and RISC supplements
Abstract: The crenarchaeal order Sulfolobales collectively contains at least five major terminal oxidase complexes. Based on genome sequence information, all five complexes are found only in Metallosphaera sedula and Sulfolobus tokodaii, the two sequenced Sulfolobales capable of iron oxidization. Wh...
ORGANISM(S): Metallosphaera sedula 
2008-10-22 | E-GEOD-12044 | biostudies-arrayexpress
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