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ProteomicsExploring the targetome of IsrR, an iron-regulated sRNA controlling the synthesis of iron-containing proteins in Staphylococcus aureus
As integral parts of gene regulatory networks, small regulatory RNAs (sRNAs) play important roles in the adaptation of bacteria to environmental conditions. To adapt to iron limitation, many bacteria exploit an "iron-sparing" response mediated by Fur-regulated sRNAs such as RyhB of E. coli, allowing...
ORGANISM(S): Staphylococcus aureus 
2024-07-12 | PXD045218 | Pride
Hg001 Iron limitation Staphylococcus aureus Iron sparing response Isrr 
TranscriptomicsTranscription profiling of E. coli wild type and Fur mutant strains ectopically expressing RyhB to investigate global iron use
RyhB is a non-coding RNA regulated by the Fur repressor. It has previously been shown to cause the rapid degradation of a number of mRNAs that encode proteins that utilize iron. Here we examine the effect of ectopic RyhB production on global gene expression by microarray analysis. Many of the pre...
ORGANISM(S): Escherichia coli 
2007-09-21 | E-GEOD-3105 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Mycobacterium avium subsp. paratuberculosis cattle and sheep strains grown under in vitro iron limiting or iron sufficient conditions
Transcriptional responses of two strain types of Mycobacterium avium subsp. paratuberculosis (MAP, cattle and sheep Strain) under in vitro iron limiting or iron sufficient growth conditions. Background: In MAP, the transcriptional role and essentiality of MAP2827 (IdeR) as an iron dependent regulato...
ORGANISM(S): Mycobacterium avium subsp. paratuberculosis 
2010-10-31 | E-MEXP-2865 | biostudies-arrayexpress
TranscriptomicsComparison of expression profiles for Agrobacterium tumefaciens wild-type strain C58 grown with or without iron.
The plant pathogen Agrobacterium tumefaciens attaches to and forms biofilms on both biotic and abiotic surfaces. The transition between free-living, planktonic A. tumefaciens and multicellular biofilms is regulated by several well-defined environmental and nutritional inputs, including pH, oxygen te...
ORGANISM(S): Agrobacterium tumefaciens 
2015-07-22 | E-GEOD-71138 | biostudies-arrayexpress
UnknownsRNA-controlled iron sparing response in Staphylococci.
Not available
S-EPMC9410917 | biostudies-literature
UnknownA global investigation of the Bacillus subtilis iron-sparing response identifies major changes in metabolism.
Not available
S-EPMC3347201 | biostudies-literature
UnknownThe Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.
Not available
S-EPMC2575260 | biostudies-literature
UnknownSmall RNA profiling in Mycobacterium tuberculosis identifies MrsI as necessary for an anticipatory iron sparing response.
Not available
S-EPMC6016810 | biostudies-literature
TranscriptomicsThe Graded Response of Fur Regulon to Iron Limitation in Bacillus subtilis
Bacterial cells often modulate their transcriptional profiles in response to the changes in iron availability. Ferric uptake regulator (Fur), as a global iron biosensor, plays a central role in maintaining iron homeostasis in Bacillus subtilis. Here we utilized a high affinity Fe2+ efflux transporte...
ORGANISM(S): Bacillus subtilis 
2017-06-30 | GSE100668 | GEO
ProteomicsThe iron-regulated sRNA IsrR is involved in the display of full Staphylococcus aureus virulence in part via SaeRS activation
The Gram-positive pathogenic bacterium Staphylococcus aureus permanently colonizes the nasal mucosa in about 30% of the healthy population. However, as an opportunistic pathogen, S. aureus can also cause a variety of diseases, the treatment of which is becoming increasingly difficult due to antibiot...
ORGANISM(S): Staphylococcus aureus 
2025-04-11 | PXD055092 | Pride
Saers Virulence Staphylococcus aureus Secretome Isrr 
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