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MetabolomicsX-ray Irradiation Suppresses Keloid Growth by Inducing G2/M Arrest via the Phytosphingosine-KIF20A Axis
Keloid radiotherapy is clinically effective but has an incomplete underlying molecular mechanism and limited accessibility; we used X-ray exposure to identify effector pathways replicating its antifibrotic benefits without further radiation. After collecting patient keloid samples, primary human kel...
2026-06-06 | MTBLS14461 | MetaboLights
MetabolomicsThe effect of transplanted mouse feces on serum metabolites of recipient mice after ionizing radiation irradiation
Collect feces from mice exposed to ionizing radiation at 1 week, 2 weeks, 3 weeks, and 4 weeks respectively. After treatment with compound antibiotics, transplant the feces of mice irradiated with ionizing radiation, collect serum from recipient mice, and detect the content of metabolites.
2026-09-28 | MTBLS15756 | MetaboLights
TranscriptomicsGene expression profile of bone marrow with post-irradiation radioprotector
To elucidate the mechanism of the in vivo radioprotection activity of Zn-containing heat-treated Saccharomyces cerevisiae yeast (Zn-yeast), expression changes in bone marrow after whole body irradiation (WBI) with concomitant treatment of Zn-yeast were analyzed using microarray technology. Keywords...
ORGANISM(S): Mus musculus 
2010-09-27 | E-GEOD-18727 | biostudies-arrayexpress
ProteomicsMulti-omics metabolism analysis on irradiation-induced oxidative stress to Rhodotorula glutinis
Oxidative stress is induced by various natural abiotic factors including irradiation among many microorganisms and has been demonstrated that it significantly improved growth rate and lipid production of R. glutinis. However, the specific mechanisms of how irradiation influence the metabolism of R. ...
ORGANISM(S): Rhodotorula glutinis 
2018-10-25 | PXD009678 | Pride
Rhodotorula glutinis  irradiation  stress response  multi-omics analysis 
ProteomicsQuantitative Proteomics analysis of LX-2 Responses to Irradiation and TGF-β1 Description
The human hepatic stellate cell line LX2 was treated with 8 Gy X-ray irradiation and/or 2ng/ml recombinant human TGF-β1. The iTRAQ-based high throughput quantitative proteomic approach was used to obtain a comprehensive view of the protein ensembles affected by irradiation and/or TGF-β1 treatment on...
ORGANISM(S): Homo sapiens (Human) 
2018-12-04 | PXD011242 | Pride
Hepatic stellate cell Itraq Irradiation 
ProteomicsCranial Irradiation Impairs Juvenile Social Behavior and Modulates Hippocampal Physiology
Cranial and craniospinal irradiation are the oldest central nervous system prophylaxis treatments considered for pediatric patients with lymphoblastic leukemia (ALL). However, survivors of childhood ALL that received cranial radiotherapy are at increased risk for deficits in neurocognitive skills. ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD017596 | Pride
Hippocampus Irradiation Dendritic spines 
MetabolomicsIrradiation causes alterations of polyamine, purine and sulfur metabolism in red blood cells and multiple organs (Prestool)
Not available
ORGANISM(S): Mus musculus 
ST002033 | MetabolomicsWorkbench
MetabolomicsIrradiation causes alterations of polyamine, purine and sulfur metabolism in red blood cells and multiple organs (Liver)
Not available
ORGANISM(S): Mus musculus 
ST002037 | MetabolomicsWorkbench
MetabolomicsIrradiation causes alterations of polyamine, purine and sulfur metabolism in red blood cells and multiple organs (Spleen)
Not available
ORGANISM(S): Mus musculus 
ST002041 | MetabolomicsWorkbench
MetabolomicsIrradiation causes alterations of polyamine, purine and sulfur metabolism in red blood cells and multiple organs (Kidney)
Not available
ORGANISM(S): Mus musculus 
ST002036 | MetabolomicsWorkbench
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