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ProteomicsMass spectrometry-based Quantitative RNA Modification Mapping Using Isobaric Tandem Mass Tags
Here, we present an RNA-specific isobaric tandem mass tagging (RMT) approach that enables the quantitative mapping of RNA modifications at an omics scale with high chemical accuracy. These RNA mass tags, derived and optimized from proteomics isobaric tags, are incorporated into an end-to-end workflo...
ORGANISM(S): Pseudomonas aeruginosa (strain UCBPP-PA14) 
2026-07-01 | PXD066919 | Pride
Rna modification Tmt Tandem mass tags Itraq 
UnknownImproved isobaric tandem mass tag quantification by ion mobility mass spectrometry.
Not available
S-EPMC4000571 | biostudies-literature
ProteomicsRatio accuracy evaluation and correction using tandem mass tags
The multiplexing capabilities of isobaric mass tag based protein quantification, such as Tandem Mass Tags (TMT) or Isobaric Tag for Relative and Absolute Quantitation (iTRAQ) have dramatically increased the scope of Mass Spectrometry (MS) based proteomics studies. Not only does the technology allow ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-27 | MSV000082855 | MassIVE
ProteomicsExtending the Separation Space with Trapped Ion Mobility Spectrometry Improves the Accuracy of Isobaric Tag-based Quantitation in Proteomic LC/MS/MS
Two-dimensional separation by nano-LC and trapped ion mobility spectrometry (TIMS) prior to Q-TOF tandem mass spectrometry significantly improves the accuracy of isobaric tag-based quantitation in proteome analysis without the need for additional measurement time for TIMS insertion. The obtained pea...
ORGANISM(S): Cellular Organisms 
2020-05-22 | PXD018650 | JPOST Repository
ProteomicsRatio accuracy evaluation and correction using tandem mass tags
The multiplexing capabilities of isobaric mass tag based protein quantification, such as Tandem Mass Tags (TMT) or Isobaric Tag for Relative and Absolute Quantitation (iTRAQ) have dramatically increased the scope of Mass Spectrometry (MS) based proteomics studies. Not only does the technology allow ...
ORGANISM(S): Homo sapiens (Human) 
2016-07-01 | PXD003346 | Pride
Hcd Tandem mass tags Quantitative mass spectrometry Label-free quantification 
ProteomicsDetecting single amino acids and small peptides by combining isobaric tags and peptidomics
Single amino acids and small endogenous peptides play important roles in maintaining a properly functioning organism. These molecules are however currently only routinely identified in targeted approaches. In a small proof-of-concept mass spectrometry experiment we found that by combining isobaric t...
ORGANISM(S): Homo sapiens (Human) 
2019-06-26 | PXD012872 | Pride
Cerebrospinal fluid Tmt Isobaric peptidomics Peptidomics Tandem mass tag 
UnknownGlycan analysis by isobaric aldehyde reactive tags and mass spectrometry.
Not available
S-EPMC3785247 | biostudies-literature
ProteomicsTMTpro: Design and initial evaluation of a novel Proline-based isobaric 16-plex Tandem Mass Tag reagent set
The design and synthesis of a novel proline-reporter-based isobaric Tandem Mass Tag 16 tag set (TMTpro) was carried out and the data uploaded here is a comparison of the performance of the new TMTpro tags with the current commercially available dimethylpiperidine-reporter-based TMT10/11 reagents. Da...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) Rattus norvegicus (Rat) 
2019-11-25 | PXD014750 | Pride
Tmt Tmtpro 
UnknownRelative Quantitation of Neuropeptides at Multiple Developmental Stages of the American Lobster Using N, N-Dimethyl Leucine Isobaric Tandem Mass Tags.
Not available
S-EPMC6081261 | biostudies-literature
UnknownHigh-resolution enabled 12-plex DiLeu isobaric tags for quantitative proteomics.
Not available
S-EPMC4318621 | biostudies-literature
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