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MetabolomicsLinking soil biology and chemistry in biological soil crust using isolate exometabolomics
Metagenomic sequencing provides a window into microbial community structure and metabolic potential; however, linking these data to exogenous metabolites that microorganisms process and produce (the exometabolome) remains challenging. Previously, we observed strong exometabolite niche partitioning a...
2018-07-31 | MTBLS492 | MetaboLights
MetabolomicsExploring the Interspecific Interactions and the Metabolome of the Soil Isolate Hylemonella gracilis
Analysis of aquatic microbial communities revealed that parts of its diversity consist of bacteria with cell sizes of ~0.1 μm. Such bacteria can show genomic reductions and metabolic dependencies with other bacteria. So far, no study investigated if such bacteria exist in terrestrial environments e....
2022-12-14 | MTBLS5841 | MetaboLights
MetabolomicsPb Stress and Ectomycorrhizas: Strong Protective Proteomic Responses in Poplar Roots Inoculated with Paxillus involutus Isolate and Characterized by Low Root Colonization Intensity
The commonly observed increased heavy metal tolerance of ectomycorrhized plants is usually linked with the protective role of the fungal hyphae covering colonized plant root tips. However, the molecular tolerance mechanisms in heavy metal stressed low-colonized ectormyocrrhizal plants characterized ...
2022-01-11 | MTBLS1847 | MetaboLights
TranscriptomicsLactobacillus plantarum IMDO 130201, a wheat sourdough isolate, adapts to growth in wheat sourdough simulation medium at different pH values through differential gene expression
Sourdough is a very competitive and challenging environment for microorganisms. Usually, a stable microbiota composed of lactic acid bacteria (LAB) and yeasts comes to dominate this ecosystem. Although rich in carbohydrates, thus providing an ideal environment to grow, the low pH presents a particul...
ORGANISM(S): Lactobacillus plantarum 
2011-07-31 | E-GEOD-23945 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of an azole-resistant Candida parapsilosis isolate [voriconazole].
Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of voriconazole. Whole genome microarrays were used to compare the transcriptional response of the voriconizole-resistant and susceptible isolates. Transcriptional profile of an in vitro derived ...
ORGANISM(S): Candida parapsilosis 
2011-04-18 | E-GEOD-27408 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of an azole-resistant Candida parapsilosis isolate [posaconazole].
Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of posaconazole. Whole genome microarrays were used to compare the transcriptional response of the posaconazole-resistant and susceptible isolates. Transcriptional profile of an in vitro derived ...
ORGANISM(S): Candida parapsilosis 
2011-04-18 | E-GEOD-27407 | biostudies-arrayexpress
TranscriptomicsMutation in Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Fluconazole Resistance
In the pathogenic yeast Candida albicans, the zinc cluster transcription factor Upc2p has been shown to regulate expression of ERG11 and other genes involved in ergosterol biosynthesis upon exposure to azole antifungals. ERG11 encodes lanosterol demethylase, the target enzyme of this antifungal cla...
ORGANISM(S): Candida albicans 
2008-11-04 | E-GEOD-11320 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of an azole-resistant Candida parapsilosis isolate.
This SuperSeries is composed of the following subset Series: GSE27405: Transcriptional response of an azole-resistant Candida parapsilosis isolate [fluconazole]. GSE27407: Transcriptional response of an azole-resistant Candida parapsilosis isolate [posaconazole]. GSE27408: Transcriptional response o...
ORGANISM(S): Candida parapsilosis 
2011-04-18 | E-GEOD-27409 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of an azole-resistant Candida parapsilosis isolate [fluconazole].
Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of fluconazole. Whole genome microarrays were used to compare the transcriptional response of the fluconazole-resistant and susceptible isolates. Transcriptional profile of in vitro derived fluco...
ORGANISM(S): Candida parapsilosis 
2011-04-18 | E-GEOD-27405 | biostudies-arrayexpress
ProteomicsProteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome
In this study, we isolated secreted extracellular vesicles (EVs) from a Kenyan P. falciparum clinical isolate (referred to as 9605) adapted to in vitro culture for a short period and characterized their protein content by mass spectrometry.
ORGANISM(S): Plasmodium falciparum 
2017-07-21 | PXD006925 | Pride
Lc-msms Malaria Plasmodium falciparum 
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