Sort   by:  
 Page size 
ProteomicsO-GlcNAcylation of Raptor transduces glucose signals to mTORC1
Complex molecular mechanisms ensure cellular homeostasis between nutrient sensing and energy metabolism. Strong evidence from many laboratories supports a role for the hexosamine biosynthetic pathway (HBP) and its end product, UDP-GlcNAc, as important nutrient sensors. Isotopic photocleavable taggin...
ORGANISM(S): Homo sapiens (Human) 
2023-08-03 | PXD039536 | Pride
Mtorc1 Raptor Isoptop Glucose O-glcnac 
ProteomicsCharacterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model
ALS is a devastating motor neuron disease. Protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification has been found to affect the processing of several important proteins implicated in ALS. However, the O-GlcNAcylated proteome remains unexplored during ALS progression. Herein, we probed the dyn...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD059664 | Pride
Amyotrophic lateral sclerosis (als) Sod1-g93a mice O-linked β-n-acetylglucosamine (o-glcnac) Lc-ms/ms 
Sort   by:  
 Page size