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Mass spectrometry imaging (MSI) visualises molecular distributions throughout tissues but is blind to dynamic metabolic processes. Here, MSI with high mass resolution together with multiple stable isotope labelling provided spatial analyses of phosphatidylcholine (PC) metabolism in mouse lungs. D...

2020-10-30 | MTBLS2075 | MetaboLights
Quantitative and In-Depth Survey of the Isotopic Abundance Distribution Errors in Shotgun Proteomics
ORGANISM(S): Homo Sapiens 
2017-12-06 | PXD008428 |
Aquatic microorganisms are typically identified as either oligotrophic or copiotrophic, representing trophic strategies adapted to low or high nutrient concentrations, respectively. Here, we sought to take steps towards identifying these and additional adaptations to nutrient availability with a qua...
ORGANISM(S): marine metagenome 
We used isotopic (heavy) labelling to delineate between female and male proteins interacting in the female reproductive tract. Here, we test the efficiency of the labelling protocols on the whole body of males and females.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-09-22 | PXD025072 | Pride
Genomics
Methanogenic isotopic signatures
Isotopic model of ethanolamine metabolism in E. coli, used for 13C-flux calculations.
2024-06-28 | MODEL2403010002 | BioModels
Alzheimer’s disease (AD) is the most common form of dementia and one of the leading causes of death in the United States. In past decades, extensive efforts have been devoted to improving our understanding of AD pathogenesis and accelerating biomarker discovery for early diagnosis and clinical treat...
ORGANISM(S): Homo sapiens (Human) 
2022-10-05 | PXD030724 | Pride
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