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TranscriptomicssiRNA profiling of human synovial fibroblasts depleted for clusterin
Analysis of synoviocytes cell form patients suffering of Rheumatoid arthritis and depleted for clusterin by siRNA knockdown. Note: this experiment was reloaded into ArrayExpress on 2nd December 2009 because the incorrect array design had originally been selected. The identifiers in the datafile wer...
ORGANISM(S): Homo sapiens 
2009-12-04 | E-TABM-653 | biostudies-arrayexpress
ProteomicsStructural analysis of human Clusterin/ApoJ, part 1
The conserved human secreted glycoprotein Clusterin (aka Apolipoprotein-J, ApoJ) is an abundant component of body fluids such as blood plasma and cerebrospinal fluid. Clusterin is thought to function as an extracellular molecular chaperone stabilizing misfolded proteins in solution. In addition, c...
ORGANISM(S): Homo sapiens (Human) 
2025-07-22 | PXD057022 | Pride
Human Cerebrospinal fluid Hydrogen-deuterium exchange Limited proteolysis Apolipoprotein Plasma Extracellular chaperone Rational mutagenesis 
TranscriptomicsTranscription profiling of rat fibroblasts transformed with HRAS and treated with the demethylating agent 5-aza-2-deoxycytidine
Silencing of gene expression by methylation of CpG islands in regulatory elements is frequently observed in cancer. However, an influence of the most common oncogenic signalling pathways onto DNA methylation has not yet been investigated thoroughly. To address this issue, we identified genes suppres...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-4427 | biostudies-arrayexpress
GenomicsmiRNAs in RPE cells treated by clusterin
Clusterin has been indicated to protect human retinal pigment epithelial (RPE) cells from oxidative stress-induced apoptosis. This study was conducted to identify aberrantly expressed microRNAs (miRNAs) downstream clusterin in RPE cells.
ORGANISM(S): Homo sapiens 
2016-09-21 | GSE87115 | GEO
GenomicsExercise plasma dampens brain inflammation via clusterin and boosts memory
Exercise plasma dampens brain inflammation via clusterin and boosts memory
PRJNA690545 | ENA
ProteomicsIdentification of a novel bile marker Clusterin and a public online prediction platform based on deep learning for Cholangiocarcinoma
Identification of a novel bile marker Clusterin and a public online prediction platform based on deep learning for Cholangiocarcinoma
ORGANISM(S): Homo Sapiens 
2023-07-13 | PXD043745 |
UnknownClusterin Impairs Hepatic Insulin Sensitivity and Adipocyte Clusterin Associates With Cardiometabolic Risk.
Not available
S-EPMC6385696 | biostudies-literature
ProteomicsDe-2-hydroxyisobutyrylation of clusterin attenuates neuropathology and memory deficits in an Alzheimer's disease mouse model
Backgroud Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder for which there is currently no cure, representing a serious clinical challenge. Lysine 2-hydroxyisobutyrylation (Khib) is a newly discovered post-translational modification that has been found to be wid...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-04 | PXD066261 | Pride
Clusterin Adeno-associated viruse 2-hydroxyisobutyrylation Post-translational modification Alzheimer's disease 
GenomicsGlycosylated clusterin species facilitate amyloid beta toxicity in human neurons.
Glycosylated clusterin species facilitate amyloid beta toxicity in human neurons.
PRJNA855866 | ENA
GenomicsClusterin is protective for liver fibrosis through mesothelial-specific LRP2 receptor mediated endocytosis
Clusterin is protective for liver fibrosis through mesothelial-specific LRP2 receptor mediated endocytosis
PRJNA985580 | ENA
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