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MetabolomicsMass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers

Mass spectrometry imaging (MSI) visualises molecular distributions throughout tissues but is blind to dynamic metabolic processes. Here, MSI with high mass resolution together with multiple stable isotope labelling provided spatial analyses of phosphatidylcholine (PC) metabolism in mouse lungs. D...

2020-10-30 | MTBLS2075 | MetaboLights
MetabolomicsX13CMS: Global Tracking of Isotopic Labels in Untargeted Metabolomics
Not available
ORGANISM(S): Rattus norvegicus 
ST001744 | MetabolomicsWorkbench
MetabolomicsDirect infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control
Direct-infusion mass spectrometry (DIMS) metabolomics is an important approach for characterising molecular responses of organisms to disease, drugs and the environment. Increasingly large-scale metabolomics studies are being conducted, necessitating improvements in both bioanalytical and computatio...
2022-05-16 | MTBLS79 | MetaboLights
TranscriptomicsPhylogenetic patterns in the microbial response to resource availability: amino acid incorporation in San Francisco Bay
Aquatic microorganisms are typically identified as either oligotrophic or copiotrophic, representing trophic strategies adapted to low or high nutrient concentrations, respectively. Here, we sought to take steps towards identifying these and additional adaptations to nutrient availability with a qua...
ORGANISM(S): marine metagenome 
2014-03-26 | E-GEOD-56119 | biostudies-arrayexpress
MetabolomicsCoupling between high-resolution mass spectrometry and focalized data-analysis methods provides the identification of new putative glycosidic non-anthocyanic flavonoids in grape

INTRODUCTION: The biochemical diversity of flavonoids is based on glycosylation, methylation, acylation, and many other modifications of the flavonoid backbone. Liquid chromatography coupled to high-resolution mass spectrometry demonstrated to be a powerful approach to gain new i...

2022-06-29 | MTBLS4202 | MetaboLights
ProteomicsQuantitative and In-Depth Survey of the Isotopic Abundance Distribution Errors
Quantitative and In-Depth Survey of the Isotopic Abundance Distribution Errors in Shotgun Proteomics
ORGANISM(S): Homo Sapiens 
2017-12-06 | PXD008428 |
MetabolomicsSoftware tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values

BACKGROUND: Lipidomics, the comprehensive measurement of lipids within a biological system or substrate, is an emerging field with significant potential for improving clinical diagnosis and our understanding of health and disease. While lipids diverse biological roles contribute ...

2022-05-17 | MTBLS710 | MetaboLights
MetabolomicsNon-targeted multimodal metabolomics and lipidomics data from ovine rumen fluid fractions

From an animal production and health perspective, our understanding of the metabolites in ruminant biofluids, particularly rumen fluid across different host species is poorly understood. Metabolomics is a powerful and sensitive approach for investigating low molecular weight metabolite profiles p...

2021-08-23 | MTBLS1717 | MetaboLights
ProteomicsEfficiency of isotopic labbeling in whole Drosophila body
We used isotopic (heavy) labelling to delineate between female and male proteins interacting in the female reproductive tract. Here, we test the efficiency of the labelling protocols on the whole body of males and females.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-09-22 | PXD025072 | Pride
Isotopic labelling Drosophila Sex Reproduction 
MetabolomicsInhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control - LC-MS/MS data

The global type 2 diabetes epidemic is a major health crisis and there is a critical need for innovative strategies to fight it. Although the microbiome plays important roles in the onset of insulin resistance (IR) and low-grade inflammation, the microbial compounds regulating these phenomena rem...

2025-10-20 | MTBLS12975 | MetaboLights
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