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UnknownTrp1250, Lys1252, and Arg1367 of ADAMTS13 comprise a hot spot for anti-CUB domain antibodies in patients with iTTP.
Not available
S-EPMC12597635 | biostudies-literature
ProteomicsA red blood cell-based antigen delivery system to facilitate T cell epitope presentation to induce peripheral tolerance to ADAMTS13 in immune-mediated TTP
Aims Leveraging the tolerogenic nature of their natural clearance pathway, we aim to exploit red blood cells (RBCs) as an antigen delivery system to achieve persistent exposure to ADAMTS13-derived peptides, promoting antigen-specific attenuation of autoreactive CD4+ T cells and induction of regulato...
ORGANISM(S): Homo sapiens (Human) 
2025-07-25 | PXD064980 | Pride
Adamts13 Ittp Immunopeptidomics Antigen presentation 
UnknownManagement of acquired, immune thrombocytopenic purpura (iTTP): beyond the acute phase.
Not available
S-EPMC9340390 | biostudies-literature
UnknownImmune-mediated thrombotic thrombocytopenic purpura with systemic lupus erythematosus: clinical features and outcome.
Not available
S-EPMC12306328 | biostudies-literature
UnknownRace, rituximab, and relapse in TTP.
Not available
S-EPMC9710186 | biostudies-literature
UnknownClinical, biological, prognostic characteristics of patients with immune-mediated thrombotic thrombocytopenic purpura and Sjogren's disease.
Not available
S-EPMC11367322 | biostudies-literature
TranscriptomicsGene Expression Profile during human CD4+ T cell differentiation
Subpopulations of human fetal thymocyte and circulating naïve T cells were obtained through FACS sorting, including CD3-CD4+CD8- intrathymic T progenitor cells (ITTP), CD3intCD4+CD8+ "double positive" thymocytes (DP), CD3highCD4+CD8- "single positive" thymocytes (SP4), CD3+CD4+CD8-CD45RA+CD62L+ naïv...
ORGANISM(S): Homo sapiens 
2004-07-01 | GSE1460 | GEO
TranscriptomicsTranscription profiling of human fetal thymocytes and circulating naive T cells
Subpopulations of human fetal thymocyte and circulating naïve T cells were obtained through FACS sorting, including CD3-CD4+CD8- intrathymic T progenitor cells (ITTP), CD3intCD4+CD8+ "double positive" thymocytes (DP), CD3highCD4+CD8- "single positive" thymocytes (SP4), CD3+CD4+CD8-CD45RA+CD62L+ naÃ...
ORGANISM(S): Homo sapiens 
2007-08-06 | E-GEOD-1460 | biostudies-arrayexpress
UnknownHealth-related quality of life and mental health in autoimmune thrombotic thrombocytopenic purpura patients in the caplacizumab era.
Not available
S-EPMC12804100 | biostudies-literature
UnknownExome Sequencing Identifies Abnormalities in Glycosylation and ANKRD36C in Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura.
Not available
S-EPMC8091491 | biostudies-literature
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