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ProteomicsLC-MS/MS of mouse hepatocytes sorted by lobule layers
Hepatocytes of the mammalian liver are organized in liver lobules and operate in a spatially-dependent manner. Cells in different positions along the lobule’s porto-cenrtal axis, defined by the directionality of blood flow, express different genes and perform different liver tasks. Gradients of the ...
ORGANISM(S): Mus musculus (Mouse) 
2019-08-06 | PXD014512 | Pride
Hepatocytes Liver zonation Mouse Lc-ms/ms 
ProteomicsSpatial discordances between mRNAs and proteins in the intestinal epithelium
We obtained a spatial measurement of RNA and Proteins in the small intestinal epithelium along the crypt-villus axis. We found that both were spatially heterogeneous, yet often spatially anti-correlated. We developed a Bayesian approach to infer protein translation and degradation rates from the com...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD024906 | Pride
Proteomics Small intestine  epithelium  crypt-villus axis  spatial heterogeneity  rna-protein dynamics  bayesian modeling 
Proteomics,MultiomicsMm_Stem_cell_dimethyl_ETD
Mouse Lgr5+ s stem cell, dimethyl labeling ETD
ORGANISM(S): Mus Musculus 
2012-12-31 | PAe003968 | PeptideAtlas
Proteomics,MultiomicsMm_Stem_cell_dimethyl_HCD
Mouse Lgr5+ s stem cell, dimethyl labeling HCD
ORGANISM(S): Mus Musculus 
2012-12-31 | PAe003967 | PeptideAtlas
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