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ProteomicsUPS2 Orbitrap data from Dicker, Lin and Ivanov (PMID: 20823122)
These raw data were first introduced in "Increased Power for the Analysis of Label-free LC-MS/MS Proteomics Data by Combining Spectral Counts and Peptide Peak Attributes" by Lee Dicker, Xihong Lin, and Alexander R. Ivanov (PubMed ID 20823122) (doi 10.1074/mcp.M110.002774). They represent the Sigma ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-10 | MSV000078520 | MassIVE
MetabolomicsComprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compare...
2015-11-19 | MTBLS143 | MetaboLights
UnknownHeat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae.
Not available
S-EPMC3581570 | biostudies-literature
UnknownHIV-1 Reverse Transcriptase Expression in HPV16-Infected Epidermoid Carcinoma Cells Alters E6 Expression and Cellular Metabolism, and Induces a Hybrid Epithelial/Mesenchymal Cell Phenotype.
Not available
S-EPMC10892743 | biostudies-literature
TranscriptomicsDisease Severity and Immune Activity Relate to Inter-Kingdom Gut Microbiome States in Ethnically Distinct Ulcerative Colitis Patients
Significant gut microbiota heterogeneity exists amongst UC patients though the clinical implications of this variance are unknown. European and South Asian UC patients exhibit distinct disease risk alleles, many of which regulate immune function and relate to variation in gut microbiota β-diversity...
ORGANISM(S): human gut metagenome 
2016-07-25 | E-GEOD-78724 | biostudies-arrayexpress
UnknownComprehensive Biological and Chemical Evaluation of Two <i>Seseli</i> Species (<i>S. gummiferum</i> and <i>S. transcaucasicum</i>).
Not available
S-EPMC8532678 | biostudies-literature
TranscriptomicsTranscriptional profiling of blood exposure response gene signature across clinical studies on The Tobacco Heating System 2.2 (THS 2.2) dataset 2
As part of current harm reduction strategies, candidate modified risk tobacco products (MRTP)s are developed to offer adult smokers who want to continue using tobacco products as an alternative to cigarettes while potentially reducing individual risk and population harm compared to smoking cigarette...
ORGANISM(S): Homo sapiens 
2019-06-30 | E-MTAB-6559 | biostudies-arrayexpress
TranscriptomicsApplication of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using a novel e-cigarette device with MESH(TM) technology (microRNA data)
We previously put forward a multi-layer systems toxicology framework for in vitro assessment of e-liquids that is meant to complement the battery of classical assays for genotoxicity testing. The framework started with the first layer to screen e-liquids for their potential toxicity, followed by the...
ORGANISM(S): Homo sapiens 
2019-11-01 | E-MTAB-7912 | biostudies-arrayexpress
TranscriptomicsApplication of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using a novel e-cigarette device with MESH(TM) technology (mRNA data)
We previously put forward a multi-layer systems toxicology framework for in vitro assessment of e-liquids that is meant to complement the battery of classical assays for genotoxicity testing. The framework started with the first layer to screen e-liquids for their potential toxicity, followed by the...
ORGANISM(S): Homo sapiens 
2019-11-01 | E-MTAB-7911 | biostudies-arrayexpress
ProteomicsHigh throughput microfluidic 3D biomimetic model enabling quantitative description of human breast tumor microenvironment
Cancer is driven by genetic aberrations in the tumor cells and fundamental changes in the tumor microenvironment (TME). These changes offer potential targets for novel therapeutics, yet lack of in vitro 3D models recapitulating this complex microenvironment impedes such progress. Here, we generated ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD021509 | Pride
Breast cancer Microfluidics Tumor microenvironment Proteomic profiling Alginate 
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