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Human intestinal organoids were grown in a typical 3D matrigel culture environment, or in an alginate gel, then a subset from each condition were xenotransplanted to vascularized and mature in vivo. Epithelium was isolated and epithelial only organoids (enteroids) were then grown from each condition...
ORGANISM(S): Homo sapiens 
Based on the genome sequencing and gene annotation, we analyzed the alginate lyases and other genes related to alginate metabolism of strain Vibrio sp. C42, with the highest alginate-degrading activity. Combined with proteome measurement, we proposed its alginate metabolic pathways.
ORGANISM(S): Vibrio atlanticus 
2026-06-04 | PXD037554 | Pride
Based on the genome sequencing and gene annotation, we analyzed the alginate lyases and other genes related to alginate metabolism of strain Vibrio sp. C42, with the highest alginate-degrading activity. Combined with secretome measurement, we proposed its alginate metabolic pathways.
ORGANISM(S): Vibrio atlanticus 
2026-06-04 | PXD029037 | Pride
The biocompatibility of immunoisolation devices is a major challenge for their use in cellular therapies. Utilisation of alginate for the encapsulation of pancreatic islets as a potential cellular therapy for type 1 diabetes has shown to be limited in terms of long-term graft survival, due to perica...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD009135 | Pride
D1 multipotent mesenchymal stromal cells (D1‐MSCs,ATCC® CRL 12424TM) and genetically modified with the lentiviral vector pSIN‐EF2‐Epo‐Pur to express erythropoietin (EPO). D1‐MSCs genetically modified to release EPO were immobilized into 3D alginatepoly‐ L‐lysine‐alginate (APA) microcapsules. Since d...
ORGANISM(S): Mus musculus 
Experiment to see the effect of regular and RGD alginate on MSC derived from bone marrow and adipose tissue
ORGANISM(S): Homo sapiens 
alginate converting by MCF Metagenome
Multilayer murine follicles were grown in 3% alginate and follicles were isolated for transcriptomics analysis at day 0, 2, 4,5,6,and 8 after encapsulation. This data complements to the GSE42795, where follicles were grown in vitro in 0.5% alginate gels A total of 8 samples were analyzed, each of th...
ORGANISM(S): Mus musculus 
Ruminal degradation of alginate from brown seaweed (Saccharina latissima) through 'alginate utilization loci' in Prevotella sp.
Introduction: Autologous platelet concentrates (APC) are pro-angiogenic and can promote wound healing and tissue repair, also in combination with other biomaterials. However, challenging defect situations remain demanding. 3D bioprinting of an APC based bioink encapsulated in a hydrogel could overco...
ORGANISM(S): Homo sapiens (Human) 
2024-06-23 | PXD050629 | Pride
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