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MetabolomicsGlobal metabolomics of IFNy cued neurogenic NSCs seeded on hydrogel
Not available
ORGANISM(S): Rattus norvegicus 
ST001492 | MetabolomicsWorkbench
ProteomicsPorcine breast extracellular matrix hydrogel for spatial tissue culture
Porcine mammary fatty tissues represent an abundant source of biomaterial for generation of breast-specific extracellular matrix (ECM). Here we report the extraction of total ECM proteins from pig breast fatty tissues, the fabrication of hydrogel scaffolds from the extracted ECM proteins, the struct...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-11-12 | PXD010960 | Pride
Breast cancer Ecm Hydrogel Scaffold Porcine 3d culture 
ProteomicsTowards optimized tissue regeneration: A new 3D printable bioink of alginate/cellulose hydrogel loaded with thrombocyte concentrate
Introduction: Autologous platelet concentrates (APC) are pro-angiogenic and can promote wound healing and tissue repair, also in combination with other biomaterials. However, challenging defect situations remain demanding. 3D bioprinting of an APC based bioink encapsulated in a hydrogel could overco...
ORGANISM(S): Homo sapiens (Human) 
2024-06-23 | PXD050629 | Pride
Platelet rich fibrin Additive manufacturing Bioprinting Hydrogel Reconstruction 
ProteomicsBioactive decellularized extracellular matrix-based hydrogel supports human adipose tissue-derived stem cell maintenance and fibrocartilage phenotype
Decellularized extracellular matrix (dECM)-based hydrogels combined with hASCs could serve as an interface for studying behavior and differentiation properties in a cartilage microenvironment. In the present study, we described the behavior of hASCs cultured in a commercial dECM MatriXpec™. The prot...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-12-22 | PXD047464 | Pride
Cartilage Hydrogel Stem cells Extracellular matrix Decellularization 
TranscriptomicsSequencing data for single cells and DNA-functionalized microbeads encapsulated in hydrogel droplets.
DNA barcodes can be used to identify single cells in a sequencing data space while optical codes can be used to track single live cells in an image data space. We have developed dual image and DNA (ID)-coding, which identifies individual single cells in both live image and sequencing data spaces. Sa...
ORGANISM(S): Homo sapiens 
2023-12-11 | E-MTAB-12988 | biostudies-arrayexpress
ProteomicsOsteogenic differentiation regulation of canine periodontal ligament stem cells by hydrogel containing magnetic nanoparticles
Bone defect architecture has become an issue to resemble in scaffold properties, beside enhancing osteoinduction. Thus, a non-invasive injectable approach is proposed by using silk fibroin (SF)-based hydrogel containing magnetic nanohydroxyapatite (MHAp) and osteogenic growth peptide (OGP). This stu...
ORGANISM(S): Canis lupus lupus 
2026-05-25 | PXD063171 | Pride
Hydrogel Osteogenic Canine periodontal ligament stem cells 
TranscriptomicsRNA-Seq of mixed glial cultures grown on different growth surfaces
Biomechanical alterations of the extracellular matrix (ECM) and injury-induced or disease-induced cell loss are major contributors to pathological astrocyte activation (astrogliosis) in the CNS and the formation of glial scars. This in vitro experiment is intended to identify transcriptional alterat...
ORGANISM(S): Mus musculus 
2026-06-29 | E-MTAB-17287 | biostudies-arrayexpress
ProteomicsThe influence of amniotic membrane proteins delivered directly or through hydrogel platforms on corneal regeneration
Purpose: This study has been aimed to investigate corneal wound healing facilitated by two hydrogels loaded with proteins derived from human amniotic membranes (AMs). Methods: Alkaline burns (8 mm diameter) were induced in the corneas of anesthetized male New Zealand White rabbits (n=44) using circu...
ORGANISM(S): Homo sapiens (Human) 
2025-02-11 | PXD055969 | Pride
Wound healing Amniotic membrane Hydrogel inserts Cornea Rabbit 
ProteomicsSilk-based hydrogel incorporated with metal-organic framework nanozymes for enhanced osteochondral regeneration
Osteochondral defects (OCD) cannot be efficiently repaired due to the unique physical architecture and the pathological microenvironment including enhanced oxidative stress and inflammation. Conventional strategies, such as the control of implant microstructure or the introduction of growth factors,...
ORGANISM(S): Rattus Norvegicus Mus Musculus 
2022-03-04 | PXD031852 |
TranscriptomicsRNAseq analysis of mouse Eph4 mammary epithelial cells to determine their response to altered extracellular matrix stiffness
Almost all cells respond to the mechanical stiffness of their microenvironment through alter gene expression. Mammary epithelial cells respond to the mechanics of the extracellular matrix (ECM) in a way that can alter their behaviour and be pro-oncogenic. How increased ECM stiffness promotes transfo...
ORGANISM(S): Mus musculus 
2025-10-22 | E-MTAB-15122 | biostudies-arrayexpress
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