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MetabolomicsEndo- and Exometabolome Crosstalk in Mesenchymal Stem Cells Undergoing Osteogenic Differentiation (Lipid Samples)
Not available
ORGANISM(S): Homo sapiens 
ST002142 | MetabolomicsWorkbench
MetabolomicsEndo- and Exometabolome Crosstalk in Mesenchymal Stem Cells Undergoing Osteogenic Differentiation (Media Samples)
Not available
ORGANISM(S): Homo sapiens 
ST002143 | MetabolomicsWorkbench
ProteomicsDifferent osteogenic differentiation behavior of canine mesenchymal stem cells derived from bone marrow and dental pulp: the proteomics profile
Although various sources of cMSCs show similar characteristics, they are different in osteogenic potential due to their original cellular sources. Thus, this study was designed to globally explore and analyze the in vitro differentiation potential and behavior of canine bone-marrow derived mesenchym...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2021-09-08 | PXD015512 | Pride
Osteogenic differentiation Canine bone-marrow derived mesenchymal stem cells (cbm-mscs) Canine dental pulp stem cells (cdpscs) Systems biology 
ProteomicsThe novel tRF-23 promotes osteogenic differentiation of hBMSCs and protects against bone loss in ovariectomized mice
The pathogenesis of osteoporosis is closely related to the impaired human bone marrow-derived stromal cells (hBMSCs) osteogenic differentiation. No studies to date, however, have established whether tRNA-derived fragments (tRFs) can influence osteogenic differentiation of hBMSCs or the onset of oste...
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD067728 | Pride
Trf-23 Osteogenic differentiation Hbmscs Osteoporosis 
ProteomicsCrenigacestat inhibits osteogenic differentiation of human valve interstitial cells and seems promising for treatment of cardiovascular calcification
Vascular calcification is common pathology various forms of which presented in the half of humans. Calcific aortic valve disease (CAVD) is one of the most dangerous forms of vascular calcification. Despite high mortality there is no target therapy against CAVD. Thus, we tested crenigacestat (LY30394...
ORGANISM(S): Homo sapiens (Human) 
2022-10-04 | PXD029632 | Pride
Valve intersticial cells Timstof pro Vascular calcification Ly3039478 Notch inhibitors Crenigacestat Calcific aortic valve disease Shotgun proteomics 
ProteomicsComparative intraindividual proteomic analysis of osteogenic differentiated adipose tissue-derived and bone marrow-derived mesenchymal stem cells reveals integrin expression profile as distinctive feature
The treatment of bone defects caused by infection, trauma or neoplasms remains a clinical challenge. Autologous bone transplantation is limited by availability, donor site morbidity and surgical risk factors. This has given rise to stromal/stem-cell based therapy. Bone marrow derived stromal cells (...
ORGANISM(S): Homo sapiens (Human) 
2021-06-09 | PXD015223 | Pride
Dia-based proteomics Bone defect Osteogenic differentiated human stem cells Integrin 
TranscriptomicsDiverse effects of cyclic AMP variants on osteogenic and adipogenic differentiation of human mesenchymal stromal cells
Osteogenic differentiation of human mesenchymal stromal cells (hMSCs) may potentially be used in cell-based bone tissue-engineering applications to enhance the bone-forming potential of these cells. Osteogenic differentiation and adipogenic differentiation are thought to be mutually exclusive, and a...
ORGANISM(S): Homo sapiens 
2018-08-05 | E-MTAB-7038 | biostudies-arrayexpress
ProteomicsComparative analysis of proteomes and secretomes of human mesenchymal stem cells isolated from six sources during osteogenic differentiation
Ability to perform osteogenic differentiation is one of the minimal criteria of mesenchymal stem cells (MSCs). Still, it is generally unknown whether osteogenic differentiation is universal cell fate or various phenotypically similar cell states. Besides this, MSCs and their secretomes are actively ...
ORGANISM(S): Homo sapiens (Human) 
2023-11-05 | PXD037320 | Pride
Msc Timstof pro Osteogenic differeniation Secretome 
TranscriptomicsTranscription profiling by array of human trabecular bone osteogenic cells
The aim of this study was to describe the gene expression patterns related to the differentiation and mineralization of bone-forming cells, including activation and/or repression of osteogenic or non-osteogenic pathways, remodeling of cell architecture, cell adhesion, cell communication, and assembl...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-12264 | biostudies-arrayexpress
TranscriptomicsPro-osteogenic trophic effects by PKA activation in human mesenchymal stromal cells
Human mesenchymal stromal cells (hMSCs) are able to differentiate into a wide variety of cell types, which makes them an interesting source for tissue engineering applications. On the other hand, these cells also secrete a broad panel of growth factors and cytokines that can exert trophic effects on...
ORGANISM(S): Homo sapiens 
2018-10-06 | E-MTAB-7224 | biostudies-arrayexpress
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