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ProteomicsThe novel tRF-23 promotes osteogenic differentiation of hBMSCs and protects against bone loss in ovariectomized mice
The pathogenesis of osteoporosis is closely related to the impaired human bone marrow-derived stromal cells (hBMSCs) osteogenic differentiation. No studies to date, however, have established whether tRNA-derived fragments (tRFs) can influence osteogenic differentiation of hBMSCs or the onset of oste...
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD067728 | Pride
Trf-23 Osteogenic differentiation Hbmscs Osteoporosis 
GenomicsThe novel tRF-23 promotes osteogenic differentiation of hBMSCs and protects against bone loss in ovariectomized mice
The pathogenesis of osteoporosis is closely related to the impaired human bone marrow-derived stromal cells (hBMSCs) osteogenic differentiation. No studies to date, however, have established whether tRNA-derived fragments (tRFs) can influence osteogenic differentiation of hBMSCs or the onset of oste...
ORGANISM(S): Homo sapiens 
2025-08-31 | GSE306555 | GEO
UnknownEvaluation of serum tRF-23-Q99P9P9NDD as a potential biomarker for the clinical diagnosis of gastric cancer.
Not available
S-EPMC9188071 | biostudies-literature
GenomicsThe novel tRF-23 promotes osteogenic differentiation of hBMSCs and protects against bone loss in ovariectomized mice
The novel tRF-23 promotes osteogenic differentiation of hBMSCs and protects against bone loss in ovariectomized mice
PRJNA1311110 | ENA
UnknownThe novel tRF-23 promotes osteogenic differentiation of hBMSCs and protects against bone loss in ovariectomized mice.
Not available
S-EPMC12790721 | biostudies-literature
GenomicsTranscriptomic analysis of human varicose veins
tRNA-derived fragments (tRFs) with a size of 15-50 nt are derived from mature or precursor tRNAs and associated with a variety of pathological conditions. However, the roles of tRFs in varicose veins (VVs) are largely unknown. The aim of this study was to identify the tRFs involved in VVs and predic...
ORGANISM(S): Homo sapiens 
2020-11-06 | GSE122109 | GEO
UnknownRNA-sequencing reveals the expression profiles of tsRNAs and their potential carcinogenic role in cholangiocarcinoma.
Not available
S-EPMC9550958 | biostudies-literature
UnknownExpression profile of tRNA‑derived fragments and their potential roles in human varicose veins.
Not available
S-EPMC6755252 | biostudies-literature
UnknownCarotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study.
Not available
S-EPMC2862308 | biostudies-literature
UnknownTransfer RNA-derived fragment tRF-28-QSZ34KRQ590K in plasma exosomes may be a potential biomarker for atopic dermatitis in pediatric patients.
Not available
S-EPMC8005743 | biostudies-literature
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