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TranscriptomicsIntegrated metabolomics, transcriptomics and proteomics identifies metabolic pathways affected by Anaplasma phagocytophilum infection in tick cells
Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human granulocytic anaplasmosis. These intracellular bacteria establish infection by affecting cell function in both the vertebrate host and the tick vector, Ixodes scapularis. Previous studies have characterized the tick transcr...
ORGANISM(S): Ixodes scapularis 
2016-01-06 | E-GEOD-68881 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of cell lines from Ixodes scapularis
The goal of this study was to identify and compare baseline mRNA expression levels for a set of Ixodes scapularis cell lines originally reported in Munderloh et al. 1994 Journal of Parasitology 80(4):533-43. Three unmodified I. scapularis cell lines were included in the study: ISE6, IDE2, and ISE18....
ORGANISM(S): Ixodes scapularis 
2024-08-15 | GSE269712 | GEO
GenomicsIxodes scapularis
Effect of Anaplasma phagocytophilum infection on the micro RNA profile of Ixodes scapularis tick cells
PRJNA315659 | ENA
GenomicsTranscriptome profiling of cell lines from Ixodes scapularis
Transcriptome profiling of cell lines from Ixodes scapularis
PRJNA1123289 | ENA
MetabolomicsCroquemort elicits activation of the immune deficiency pathway in ticks
The immune deficiency (IMD) pathway directs host defense in arthropods upon bacterial infection. In Pancrustacea, peptidoglycan recognition proteins sense microbial moieties and initiate nuclear factor-κB-driven immune responses. Proteins that elicit the IMD pathway in non-insect arthropods remain e...
2023-04-27 | MTBLS686 | MetaboLights
UnknownA draft genome sequence for the Ixodes scapularis cell line, ISE6.
Not available
S-EPMC5883391 | biostudies-literature
GenomicsIxodes ricinus
Tissue-specific signatures in the transcriptional response to Anaplasma phagocytophilum infection of Ixodes scapularis and Ixodes ricinus tick cell lines
PRJNA308910 | ENA
UnknownInduction of intracellular ferritin expression in embryo-derived Ixodes scapularis cell line (ISE6).
Not available
S-EPMC6224502 | biostudies-literature
UnknownEnlisting the Ixodes scapularis Embryonic ISE6 Cell Line to Investigate the Neuronal Basis of Tick-Pathogen Interactions.
Not available
S-EPMC7828734 | biostudies-literature
ProteomicsMetabolic pathways affected by Anaplasma in tick cells
Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human granulocytic anaplasmosis. These intracellular bacteria establish infection by affecting cell function in both the vertebrate host and the tick vector, Ixodes scapularis. Previous studies have characterized the tick transcr...
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) 
2015-10-05 | PXD002181 | Pride
Ixodes scapularis ise6 cells Anaplasma phagocytophilum Rp-lc-lit-ms 
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