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Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human granulocytic anaplasmosis. These intracellular bacteria establish infection by affecting cell function in both the vertebrate host and the tick vector, Ixodes scapularis. Previous studies have characterized the tick transcr...
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) 
2015-10-05 | PXD002181 | Pride
Current understanding of oocyte quality and developmental potential maintains that stochastic or epigenetic processes modulate the action of determinants that are laid in the oocyte during oogenesis. These determinants are considered to be rather conserved across mice, leading different strains of m...
ORGANISM(S): Mus musculus 
Glycation is a post-translational modification underlied by the interaction of protein amino and guanidino groups with carbonyl compounds like reducing sugars and α-dicarbonyls. In the first steps of this process, the protein amino groups react with reducing carbohydrates yielding the corresponding ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2017-06-19 | PXD006434 | Pride
The role played by protein turnover in metabolic reprogramming is unknown. Herein, using a SILAC approach, we have studied the changes in the half-life of two hundred and sixty-six proteins of energy metabolism and of translation during the metabolic switch induced by the prolyl hydroxylases inhibit...
ORGANISM(S): Homo sapiens (Human) 
2019-07-15 | PXD013482 | Pride
The ribosome is a translational apparatus that comprises about 80 ribosomal proteins and four rRNAs. Recent studies reported that ubiquitination of the ribosomal proteins plays a pivotal role in translational control and ribosome-associated quality control (RQC). However, little is known about the d...
ORGANISM(S): Danio Rerio 
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