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TranscriptomicsCoordinated posttranscriptional mRNA population dynamics during T-cell activation
Although RNA-binding proteins (RBPs) coordinate many key decisions during cell growth and differentiation, the dynamics of RNA–RBP interactions have not been extensively studied on a global basis. We immunoprecipitated endogenous ribonucleoprotein complexes containing HuR and PABP throughout a T-cel...
ORGANISM(S): Homo sapiens 
2009-08-19 | E-GEOD-11989 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of decidual CD8+ CCR7-CD45RA- Effector-Memory T cells
To understand the regulation of cytotoxicity by decidual CD8+ T cells (CD8+ dT) at the maternal-fetal interface, gene expression analysis of CCR7-CD45RA- effector-memory CD8+ T cells isolated from peripheral blood of unrelated healthy controls and decidual tissue from first trimester (6-12 weeks) an...
ORGANISM(S): Homo sapiens 
2017-12-19 | E-MTAB-5890 | biostudies-arrayexpress
TranscriptomicsFunctional coordination and HuR-mediated regulation of mRNA stability during T cell activation
We evaluated changes in mRNA stability and transcription using 4sU metabolic pulse labeling across a four hour time course following activation of Jurkat T cells with PMA and PHA Measurement of total mRNA (T) and 4sU labeled mRNA (IP) in three biological replicates at five time points: prior to acti...
ORGANISM(S): Homo sapiens 
2015-10-28 | E-GEOD-71382 | biostudies-arrayexpress
TranscriptomicsCo-culture of synovial tissue dendritic cells with autologous peripheral blood memory T-Cells across Active and Remission RA
To dissect the precise roles of ST-DC2 clusters and ST-iDC3 clusters in T-cell activation, we co-cultured each cluster separately with autologous memory CD4pos T-cells. FACS-sorted ST-DC2 clusters and ST-iDC3 clusters from synovial tissue of active RA or remission RA were co-cultured for 5 days wit...
ORGANISM(S): Homo sapiens 
2024-12-09 | E-MTAB-14191 | biostudies-arrayexpress
UnknownThe complete mitochondrial genome of Chilean Jack Mackerel, Trachurus murphyi Nichols, 1920 (Teleostei, Carangidae).
Not available
S-EPMC11514408 | biostudies-literature
UnknownTwo new bisindole alkaloids from Tabernaemontana macrocarpa Jack.
Not available
S-EPMC8021936 | biostudies-literature
UnknownA homozygous KCNJ10 mutation in Jack Russell Terriers and related breeds with spinocerebellar ataxia with myokymia, seizures, or both.
Not available
S-EPMC4238845 | biostudies-literature
TranscriptomicsRNA-seq of a controlled porcine model of trauma and haemorrhagic shock treated by fluid resuscitation against untreated controls
This was a randomised study in terminally anaesthetised female cross-bred Large White pigs. Initially, animals were anaesthetised and instrumented for continuous physiological monitoring and sampling; blood samples were collected upon initiation of the surgery (line-in, T = -150 minutes). Following ...
ORGANISM(S): Sus scrofa 
2026-10-28 | E-MTAB-16011 | biostudies-arrayexpress
Proteomicsmass spec raw files for the manuscript - Yang, T. et al
mass spec raw files for the manuscript - Reversible lysine-targeted probes reveal residence time-based kinase selectivity in vivo. Yang, T et al.
ORGANISM(S): Homo Sapiens 
2022-01-25 | MSV000088731 | MassIVE
TranscriptomicsExpression data from Chimeric Antigen Receptor (CAR) Expressing T cells
Human T cells isolated from healthy donors were transduced with non-tonically signaling CARs or tonically signaling CARs, each with CD28z or 4-1BB costimulatory domains Human T cells isolated from healthy donors were transduced with non-tonically signaling CARs or tonically signaling CARs, each with...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-65856 | biostudies-arrayexpress
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