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TranscriptomicsImmunoregulatory actions of epithelial cell PPAR g at the colonic mucosa
BACKGROUND: Peroxisome proliferator-activated receptor g (PPAR g) is a nuclear receptor whose activation has been shown to modulate macrophage and epithelial cell-mediated inflammation. The objective of this study was to use a systems approach for investigating the mechanism by which the deletion o...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-20621 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of Tregs from WT mice and Ccr6 KO mice
The experiment was designed to compare transcriptomic differences between WT and Ccr6 KO Tregs during activation. WT and Ccr6 KO Tregs, cells were isolated from mice and cultured in vitro for 3 days with activation using anti-CD3/CD28 beads. Total RNA was extracted using the Trizol method. Quantity ...
ORGANISM(S): Mus musculus 
2024-08-10 | E-MTAB-14288 | biostudies-arrayexpress
TranscriptomicsMpeR regulation in Neisseria gonorrhoeae (F19) through an iron-responsive mechanism
Previous studies have shown that the MpeR transcriptional regulator produced by Neisseria gonorrhoeae represses expression of mtrF, which encodes a putative inner membrane protein that works with the MtrC-MtrD-MtrE efflux pump to allow gonococci to resist high levels of multiple hydrophobic antimicr...
ORGANISM(S): Neisseria gonorrhoeae 
2012-04-03 | E-GEOD-32717 | biostudies-arrayexpress
TranscriptomicsThe genetics of splicing in neuroblastoma
Regulation of mRNA splicing is a critical and tightly regulated cellular function, underlying the majority of proteomic diversity in our genomes. While disruption of this process is common in disease, the basic genetic complexity of alternative splicing in vivo remains poorly understood. To delinea...
ORGANISM(S): Mus musculus 
2015-04-03 | E-GEOD-55248 | biostudies-arrayexpress
UnknownAssociation of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.
Not available
S-EPMC3090190 | biostudies-literature
UnknownGenome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.
Not available
S-EPMC7387190 | biostudies-literature
UnknownImpact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
Not available
S-EPMC5595282 | biostudies-literature
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
UnknownCerebral small vessel disease genomics and its implications across the lifespan.
Not available
S-EPMC7722866 | biostudies-literature
UnknownGenome-wide association study identifies eight loci associated with blood pressure.
Not available
S-EPMC2891673 | biostudies-literature
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