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TranscriptomicsTranscription profiling of bone marrow derived mast cells from WASP negative and wild type mice to investigate the role of WASP in Kit signalling
The pleiotropic RTK Kit can provide cytoskeletal signals that define cell shape, positioning and migration, but the underlying mechanisms are less well understood. Here we provide evidence that Kit signals through WASP (Wiskott-Aldrich Syndrome Protein), the central hematopoietic actin nucleation- ...
ORGANISM(S): Mus musculus 
2009-08-29 | E-MEXP-2282 | biostudies-arrayexpress
UnknownIntegrated metabolism in sponge-microbe symbiosis revealed by genome-centered metatranscriptomics.
Not available
S-EPMC5520145 | biostudies-literature
ProteomicsPhagolysosomal proteomics identifies different macrophage activation profiles in response to Aspergillus fumigatus conidia
An Aspergillus fumigatus infection is initialized by the inhalation and germination of airborne asexual spores (conidia). Alveolar macrophages are the first immune cells to counteract an infection by phagocytosis of conidia and intracellular degradation of the pathogen. However, A. fumigatus circumv...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) Mus musculus (Mouse) 
2018-03-08 | PXD005724 | Pride
Phagolysosome Macrophages Host-pathogen interaction Aspergillus fumigatus 
ProteomicsSHMT2 controls Burkitt lymphoma cell survival by maintaining an oncogenic TCF3 transcriptional program
In this study, the human Burkitt’s Lymphoma cell line BL60 has been analysed via proteomic and phosphoproteomic analysis for effect of a knock down of the serine hydroxymethyltransferase 2 (shSHMT2) compared to a control construct (shGL2). Concerning the phosphoproteome, these results have been comp...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD018961 | Pride
B cell receptor One carbon metabolism Burkitt’s lymphoma 
UnknownEfficacy and safety of maintenance intravenous immunoglobulin in generalized myasthenia gravis patients with acetylcholine receptor antibodies: A multicenter, double-blind, placebo-controlled trial.
Not available
S-EPMC11632570 | biostudies-literature
UnknownNaomi: a new modelling tool for estimating HIV epidemic indicators at the district level in sub-Saharan Africa.
Not available
S-EPMC8454682 | biostudies-literature
UnknownEstablishing standardized immune phenotyping of metastatic melanoma by digital pathology.
Not available
S-EPMC8590976 | biostudies-literature
UnknownTroponin and Cardiac Events in Stable Ischemic Heart Disease and Diabetes.
Not available
S-EPMC4627639 | biostudies-literature
UnknownSHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Not available
S-EPMC8938936 | biostudies-literature
UnknownTranscriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity.
Not available
S-EPMC10170694 | biostudies-literature
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