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UnknownTRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
Not available
S-JCBD-201503023 | bioimages
MetabolomicsHost autophagy mediates organ wasting and nutrient mobilization for tumor growth
During tumor growth-when nutrient and anabolic demands are high-autophagy supports tumor metabolism and growth through lysosomal organelle turnover and nutrient recycling. Ras-driven tumors additionally invoke non-autonomous autophagy in the microenvironment to support tumor growth, in part through ...
2021-09-24 | MTBLS2771 | MetaboLights
GenomicsA validated regulatory network for Th17 cell specification
Th17 cells have critical roles in mucosal defense and are major contributors to inflammatory disease. Their differentiation requires the nuclear hormone receptor RORγt working with multiple other essential transcription factors (TFs). We have used an iterative systems approach, combining genome-wide...
ORGANISM(S): Mus musculus 
2012-09-20 | E-GEOD-40918 | biostudies-arrayexpress
UnknownMammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs
Not available
S-SCDT-10_15252-EMBJ_2022112845 | biostudies-other
UnknownSelective Autophagy of RIPosomes Maintains Innate Immune Homeostasis during Bacterial Infection
Not available
S-SCDT-EMBOJ-2022-111289 | biostudies-other
TranscriptomicsCancer cell-endothelial intercellular transfer alters the endogenous miRNA profile and phenotype of recipient endothelial cells
Metastasis is a major cause of mortality, and remains a final frontier in the search for a cure for cancer. While there has been much research on the ‘seed’ (metastatic tumor cells) and the ‘soil’ (colonized host tissue), interactions between metastatic cancer cells and stromal endothelial cells, wh...
ORGANISM(S): Homo sapiens 
2015-09-04 | E-GEOD-72679 | biostudies-arrayexpress
UnknownAutoimmunity Gene IRGM Suppresses cGAS-STING and RIG-I-MAVS Signaling to control Interferon Response
Not available
S-SCDT-EMBOR-2020-50051V1 | biostudies-other
UnknownHost autophagy mediates organ wasting and nutrient mobilization for tumor growth
Not available
S-SCDT-EMBOJ-2020-107336 | biostudies-other
UnknownCDK12/CDK13 inhibition disrupts transcriptional elongation and fork progression in glioblastoma
Not available
S-SCDT-10_1038-S44321-026-00393-W | biostudies-other
UnknownVitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study.
Not available
S-EPMC8728359 | biostudies-literature
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