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TranscriptomicsTranscription profiling of human dendritic cells matured by cadherin reveals disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation
The maturation of dendritic cells (DCs) after exposure to microbial products or inflammatory mediators plays a critical role in initiating the immune response. We found that maturation can also occur under steady state conditions, triggered by alterations in E-cadherin-mediated DC-DC adhesion. Sele...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9241 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiles of meningiomas
Meningiomas, one of the most common human brain tumors, are derived from arachnoidal cells associated with brain meninges, usually benign and frequently associated with neurofibromatosis type 2. Here we define a human meningioma-typical miRNA profile and characterize effects of one down-regulated mi...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-17792 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of E. coli NCTC 9001 challenged with four different cationic antimicrobial peptides
Obtaining an in depth understanding of the arms races between peptides comprising the innate immune response and bacterial pathogens is of fundamental interest and will inform the development of new antibacterial therapeutics. Many cationic antimicrobial peptides (AMPs) share a range of structural a...
ORGANISM(S): Escherichia coli 
2014-01-21 | E-MTAB-1703 | biostudies-arrayexpress
MetabolomicsRapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats
INTRODUCTION: Oats (Avena sativa L.) are a whole grain cereal recognised for their health benefits and which are cultivated largely in temperate regions providing both a source of food for humans and animals, as well as being used in cosmetics and as a potential treatment for a number of...
2020-06-11 | MTBLS804 | MetaboLights
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
UnknownDiversity, distribution and ecology of fungal communities present in Antarctic lake sediments uncovered by DNA metabarcoding.
Not available
S-EPMC9120451 | biostudies-literature
UnknownTotal synthesis of [Ψ[C(═S)NH]Tpg4]vancomycin aglycon, [Ψ[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.
Not available
S-EPMC3262083 | biostudies-literature
UnknownAromatic amino acid biosynthesis impacts root hair development and symbiotic associations in Lotus japonicus.
Not available
S-EPMC10517252 | biostudies-literature
MetabolomicsIntegration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance
The development of reliable, mixed-culture biotechnological processes hinges on understanding how microbial ecosystems respond to disturbances. Here we reveal extensive phenotypic plasticity and niche complementarity in oleaginous microbial populations from a biological wastewater treatment plant. W...
2021-04-06 | MTBLS2021 | MetaboLights
TranscriptomicsMechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch
Hypoxia-induced cell injury has been related to multiple pathological conditions. In order to render hypoxia-sensitive cells and tissues resistant to low O2 environment, in this current study, we used Drosophila melanogaster as a model to dissect the mechanisms underlying hypoxia-tolerance. A D. mel...
ORGANISM(S): Drosophila melanogaster 
2010-06-25 | E-GEOD-8803 | biostudies-arrayexpress
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