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MetabolomicsMetabolic phenotyping of ex-vivo breast samples by DESI mass spectrometry imaging
This study involves the analysis of surgically resected samples from patients undergoing breast surgery. The samples published here have been used as part of the publication by [1], and all experimental details can be found within. Desorption electrospray ionisation mass spectrometry imaging (DESI M...
2016-04-28 | MTBLS273 | MetaboLights
Unknown1281. Longitudinal and Spatial Variation in the Human Microbiome in a Phase 2a Clinical Study of Gepotidacin in Adult Females with Uncomplicated Urinary Tract Infection
Not available
S-EPMC7776697 | biostudies-literature
ProteomicsLambert_BRD_SAINT2307_JQ1_APMS_time_course_TripleTOF_P82_VS5
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. More precisely, files used in the SAINT express task 2307 are in this dataset. The AP-MS experiments involv...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-25 | MSV000081006 | MassIVE
ProteomicsSAINT_3727_JQ1_APMS_endoK562_P82_VS17_28AUG2018
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. This submission contains 16 files associated with endogenous IP-MS analysis of BRD2, BRD3 and BRD4 (IgG was...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-28 | MSV000082859 | MassIVE
ProteomicsSAINT_3726_JQ1_APMS_endoHEK293_P82_VS16_28AUG2018
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. This submission contains 16 files associated with endogenous IP-MS analysis of BRD2, BRD3 and BRD4 (IgG was...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-28 | MSV000082857 | MassIVE
Metabolomics3D DESI mass spectrometry imaging of 52 serial sections from a human colorectal adenocarcinoma
Fifty-two serial sections from a single human adenocarcinama are made available in this dataset. Four neighbouring sections were placed on a single slide and analysed together. The tissue sections were analysed by desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) according to t...
2017-03-21 | MTBLS415 | MetaboLights
Metabolomics3D DESI mass spectrometry imaging of 51 serial sections from a human liver metastasis
51 serial sections from a single human liver metastasis are made available in this dataset. Four neighbouring sections were placed on a single slide and analysed together. The tissue sections were analysed by desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) according to the pr...
2016-04-28 | MTBLS282 | MetaboLights
TranscriptomicsTranscription profiling of S. cerevisiae wild type reference strain, two simple mutants (not1-2 and spt3) and one double mutant (not1-2 spt3) reveals a SAGA-Independent function of SPT3 mediates transcriptional deregulation in a mutant of the Ccr4-Not Complex
The conserved multi-subunit Ccr4-Not complex regulates gene expression in diverse ways. In this work, we characterize the suppression of temperature sensitivity associated with a mutation in the gene encoding the scaffold subunit of the Ccr4-Not complex, NOT1, by the deletion of SPT3. We determine t...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9432 | biostudies-arrayexpress
ProteomicsSmall molecule inhibition of ubiquitin C-terminal hydrolase L1 alters cell metabolism proteins and exerts anti- or pro-tumorigenic effects contingent upon chemosensitivity status in high grade serous ovarian cancer
In the current investigation, we sought to characterize the implications of UCHL1 small molecule inhibition in both chemosensitive and chemoresistant HGSOC cells, generating an unprecedented understanding of the clinically relevant implications of targeting UCHL1.
ORGANISM(S): Homo sapiens (Human) 
2025-02-26 | PXD060691 | Pride
Human Ovarian cancer Lc-ms Small molecule inhibitor 
TranscriptomicsTranscription profiling by array of lymphoblastic cells, fat and skin from twins
Gene expression was quantified in LCL, skin and fat derived from a subset of Twins UK (N=156 LCL, N=160 skin, N=166 fat) using Illuminas whole genome expression array (HumanHT-12 version 3). Cis eQTL analysis was performed in each tissue, following by multiple analyses assessing the tissue-specifici...
ORGANISM(S): Homo sapiens 
2011-02-03 | E-MTAB-522 | biostudies-arrayexpress
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