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TranscriptomicsTranscription profiling by array to assess epidemic methicillin-resistant Staphylococcus aureus 16 phenotypes induced by PBD conjugates
Objectives Pyrrolobenzodiazepine (PBD) dimers, tethered through inert propyldioxy or pentyldioxy linkers, possess potent bactericidal activity against a range of Gram-positive bacteria by virtue of their capacity to cross-link duplex DNA in sequence-selective fashion. Here we attempt to improve the ...
ORGANISM(S): Staphylococcus aureus 
2012-04-17 | E-BUGS-118 | biostudies-arrayexpress
TranscriptomicsKaplan2013: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II
Dynamic control of gene expression is crucial for most aspects of cell physiology and at its core is RNA polymerase II (RNAPII). Using 53 RNAPII point mutants, we generated a point mutant epistatic miniarray profile (pE-MAP) comprising ~60,000 quantitative genetic interactions in Saccharomyces cere...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-06 | E-GEOD-47429 | biostudies-arrayexpress
GenomicsCollaborative Association Study of Psoriasis

The goal of this collaborative study is to combine the resources and expertise of three groups with long-standing studies of psoriasis genetics in order to identify new genetic susceptibility factors for psoriasis, a common inflammatory skin disease that affects over 4 million Americans.

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phs000019.v1.p1 | EGA
TranscriptomicsRNAseq analysis of colon and ileum tissue from naive wild type, MR1-/- and IL-17A-/- mice
Determination of differentially expressed genes in the proximal colon and distal ileum tissue in MR1 and IL-17A deficiency at steady-state. Tissue from naïve mice was harvested, total RNA extracted and subjected to RNASeq analysis.
ORGANISM(S): Mus musculus 
2018-03-31 | E-MTAB-6547 | biostudies-arrayexpress
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
UnknownValidation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
Not available
S-EPMC8855527 | biostudies-literature
UnknownTwo Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition.
Not available
S-EPMC8189692 | biostudies-literature
UnknownGlobal Burden of Cardiovascular Diseases and Risks, 1990-2022.
Not available
S-EPMC7615984 | biostudies-literature
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