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GenomicsCore transcriptional regulatory circuit controlled by the tal1 complex in human t-cell acute lymphoblastic leukemia (Subseries)
The oncogenic transcription factor TAL1/SCL is aberrantly overexpressed in over 40% of cases of T-cell acute lymphoblastic leukemia (T-ALL), emphasizing the importance of the TAL1-regulated transcriptional program in the molecular pathogenesis of T-ALL. Here we identify the core transcriptional regu...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-33850 | biostudies-arrayexpress
TranscriptomicsEffect of short- and long-term morphine treatment on gene expression in the hypothalamus and pituitary
Addictive drugs including opioids activate signal transduction pathways that regulate gene expression in the brain. However, changes in CNS gene expression following morphine exposure are poorly understood. We studied the effect of short- and long-term morphine treatment on gene expression in the hy...
ORGANISM(S): Mus musculus 
2008-09-30 | E-GEOD-9525 | biostudies-arrayexpress
UnknownParallel characterization of cis-regulatory elements for multiple genes using CRISPRpath.
Not available
S-EPMC8443183 | biostudies-literature
UnknownBridging the digital divide for people with aphasia: a study protocol for codesigning web accessibility tools and guidelines
Not available
S-EPMC12336571 | biostudies-literature
UnknownHigh-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Not available
S-EPMC7002524 | biostudies-literature
TranscriptomicsResveratrol Diet Aging (Heart, Liver, Muscle and Fat Tissue)
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending lifespan A small molecule that safely mimics the ability of dietary restriction (DR) to delay age-related diseases in laboratory animals is greatly sought after. We and others ha...
ORGANISM(S): Mus musculus 
2008-08-04 | E-GEOD-11845 | biostudies-arrayexpress
UnknownNational Marrow Donor Program-Sponsored Multicenter, Phase II Trial of HLA-Mismatched Unrelated Donor Bone Marrow Transplantation Using Post-Transplant Cyclophosphamide.
Not available
S-EPMC8260905 | biostudies-literature
UnknownAmpullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation.
Not available
S-EPMC4982376 | biostudies-literature
UnknownNorovirus co-opts NINJ1 for selective protein secretion.
Not available
S-EPMC11870086 | biostudies-literature
UnknownTumour priming by ultrasound mechanogenetics for CAR T therapy.
Not available
S-EPMC12867766 | biostudies-literature
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