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We conducted a pilot label-free LC-MS/MS study to profile and compare the cerebral spinal fluid from California sea lions with domoic acid toxicosis and without domoic acid toxicosis. CSF samples from a 8 animals with DAT and 3 controls were run on a nano LC-MS/MS (Triple TOF) and searched against a...
ORGANISM(S): Zalophus californianus (California sealion) 
2015-09-21 | PXD002105 | Pride
Targeted approaches have been widely used to help explain physiological adaptations, but few studies have used non-targeted omics approaches to explore differences between diving marine mammals and terrestrial mammals. A rank comparison of undepleted serum proteins from common bottlenose dolphins (T...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2018-10-26 | PXD004967 | Pride
Feeding a modified fish diet has been suggested to improve insulin sensitivity in bottlenose dolphins; however insulin sensitivity was not directly measured. Since demonstrating an improvement in insulin sensitivity is technically difficult in dolphins, we postulated that directional changes in the ...
ORGANISM(S): Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus) 
2016-04-20 | PXD003425 | Pride
Since 1998, California sea lion stranding events associated with domoic acid toxicosis (DAT) have consistently increased and there are no practical non-lethal clinical tests for the diagnosis of domoic acid toxicosis that can be utilized in a large-scale rehabilitation facility. Proteomic analysis w...
ORGANISM(S): Zalophus californianus (California sealion) 
2023-04-05 | PXD041356 | Pride
This data is a re-analysis of samples used in a prior study (doi:10.1371/journal.pone.0123295) evaluating plasma candidate biomarkers of chronic domoic acid toxicosis (DAT) in California sea lions (Zalophus californianus). The previous study used 2D-gel electrophoresis to analyze plasma from a train...
ORGANISM(S): Zalophus californianus (California sealion) 
2020-07-17 | PXD020366 | Pride
Urinary proteins provide valuable insights into renal health, with implications spanning human and domestic animal veterinary medical research. However, the field of marine mammal medicine lacks comprehensive studies on urine protein composition. This research aimed to fill this gap by 1) selecting ...
ORGANISM(S): Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus) 
2024-08-01 | PXD054283 | Pride
Global metaproteomic analyses of microbial biomass from the upper water column of the Central Pacific Ocean. This dataset was used as a discovery dataset to identify peptide biomarkers for cyanobacterial populations for use in targeted metaproteomic calibrated multiple reaction monitoring (MRM) anal...
ORGANISM(S): Environmental Samples (ncbitaxon:318178) 
2021-11-05 | MSV000088323 | MassIVE
In 2010, the Deepwater Horizon oil spill resulted in an estimated loss of 61,000–174,000 sea turtles in the Gulf of Mexico. Rescued Kemp’s ridley sea turtle exhibited adverse effects, including physiological stress and severe derangements. While prior studies evaluated health impacts of oil exposure...
ORGANISM(S): Lepidochelys kempii 
2026-05-29 | PXD079061 | Pride
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