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Aging is the most important risk factor for the development of cardiovascular diseases. Senescent cells release plethora of factors commonly known as the senescence-associated secretory phenotype (SASP), which can modulate the normal function of the vascular wall. It is currently not well understood...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-02-13 | MSV000094069 | MassIVE
Introduction/aim: Renal cell cancer (RCC) is the most frequent kidney malignancy. Here, we aimed to analyze RCC secretome to find key molecules involved in tumor microenvironment regulation. Methods: Conditioned media from five RCC-derived cell lines (Caki-1, KIJ-265T, KIJ-308T, 786-O, and A498) and...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-02 | MSV000088490 | MassIVE
This study aimed to investigate the biological implications of two overlapping sequences in the Arabidopsis genome, the 3UTR of the PHOT2 gene and a putative AT5G58150 gene, encoded on the complementary strand. AT5G58150 is a probably inactive protein kinase that belongs to the transmembrane, leucin...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2022-12-21 | MSV000090945 | MassIVE
Nuclei were isolated from the mouse brain. Proteins were extracted with addition of Bensonase and cleaned up by acetone precipitation. Proteis were resuspended in 50 mM ammonium bicarbonate and PPS Silent Surfactant. Samples were sonicated on ice to improve the solubility of proteins, then alkylated...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
Effects of two Bcl-2 protein inhibitors Navitoclax and Venetoclax on changes in the proteome of the mouse pancreas (Mus musculus C57BL6/J, males) in a mouse model of cerulein-induced chronic pancreatitis.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
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