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Ageing and mutations of transthyretin (TTR), the thyroid hormones and retinol transporting protein lead to amyloidosis by destabilizing the structure of TTR. Because protein structure is regulated through posttranslational modifications, we investigated the Small Ubiquitin-like Modifier (SUMO)ylatio...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080754 | MassIVE
Reprogramming in protoplast cultures is a key step for acquiring embryogenic competence by dedifferentiated cells, thus leading to plant regeneration. Therefore, to better understand factors trigging the processes, this work focuses on analysing proteomes, cell wall composition and changes in the ex...
ORGANISM(S): Fagopyrum Esculentum (ncbitaxon:3617) Fagopyrum Tataricum (ncbitaxon:62330) 
Aging is the most important risk factor for the development of cardiovascular diseases. Senescent cells release plethora of factors commonly known as the senescence-associated secretory phenotype (SASP), which can modulate the normal function of the vascular wall. It is currently not well understood...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-02-13 | MSV000094069 | MassIVE
Effects of two Bcl-2 protein inhibitors Navitoclax and Venetoclax on changes in the proteome of the mouse pancreas (Mus musculus C57BL6/J, males) in a mouse model of cerulein-induced chronic pancreatitis.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
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