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ProteomicsStructural dynamics of the chicken TRPV4 N-terminal domain
Intrinsically disordered regions (IDRs) are essential for membrane receptor regulation but often remain unresolved in structural studies. TRPV4, a member of the TRP vanilloid channel family involved in thermo- and osmosensation, has a large N-terminal IDR of approximately 150 amino acids. With an in...
ORGANISM(S): Escherichia coli Gallus gallus (Chicken) 
2023-10-24 | PXD041067 | Pride
Trpv4 
TranscriptomicsMultiple DNA repair pathways collectively protect against DNA damage-induced replicative aging.
We demonstrate that transcriptomic profiling of the NER mutant ercc-1 offers better understanding of the complex phenotypes of ercc-1 deficiency in C. elegans, as it does in mammalian models. There is a transcriptomic shift in ercc-1 mutants that suggests a stochastic impairment of growth and develo...
ORGANISM(S): Caenorhabditis elegans 
2013-09-15 | E-GEOD-39145 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Arabidopsis wild type and an ARF7/ARF19 double knockout mutant roots dissected into 5 developmental zones
Arabidopsis seedlings, of both wild-type and an ARF7/ARF19 double knockout mutant, were grown to 7 days post-germination. The roots were then dissected into 5 developmental zones, the meristem, early elongation zone, late elongation zone, mature root and lateral root zone. The sections then underwen...
ORGANISM(S): Arabidopsis thaliana 
2011-04-13 | E-MEXP-2912 | biostudies-arrayexpress
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