Jdp2 - OmicsDI

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Expression data from neutrophils from wild-type and Jdp2-/- mice

Jdp2 is a member of the AP-1 family and suppresses histone acetyltransferase activity. We used microarrays to examine the gene expression pattern of neutrophil form Jdp2-/- mice. Bone marrow CD11b+Ly6Clo Ly6G+ neutrophils form wild-type and Jdp2-/-mice were sorted by FACS, followed by RNA extraction...

ORGANISM(S): Mus musculus

2012-11-30 | E-GEOD-42063 | biostudies-arrayexpress

IRF2BP2 counteracts the ATF7/JDP2 heterodimer to prevent inflammatory overactivation in AML cells

Acute myeloid leukemia (AML) is a hematological malignancy characterized by the abnormal proliferation and accumulation of immature myeloid cells in the bone marrow. Inflammation plays a crucial role in AML progression, but excessive activation of inflammatory pathways can also trigger cell death. I...

ORGANISM(S): Homo sapiens (Human)

2024-05-16 | PXD041817 | Pride