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TranscriptomicsEffects of a short-term exposure to the fungicide prochloraz on endocrine function and gene expression in female fathead minnows (Pimephales promelas)
Prochloraz is a fungicide known to cause endocrine disruption through effects on the hypothalamic-pituitary-gonadal (HPG) axis. To determine the short-term impacts of prochloraz on gene expression and steroid production, adult female fathead minnows (Pimephales promelas) were exposed to the chemical...
ORGANISM(S): Pimephales promelas 
2011-02-03 | E-GEOD-26958 | biostudies-arrayexpress
TranscriptomicsEffects of bisphenol A on ovarian gene expression in fathead minnows and zebrafish [ZF data set]
Effects of bisphenol A (BPA) on ovarian transcript profiles as well as targeted endpoints with endocrine/reproductive relevance were examined in two fish species, fathead minnow (Pimephales promelas) and zebrafish (Danio rerio), exposed in parallel using matched experimental designs. Four days of wa...
ORGANISM(S): Danio rerio 
2012-01-01 | E-GEOD-28351 | biostudies-arrayexpress
TranscriptomicsEffects of bisphenol A on ovarian gene expression in fathead minnows and zebrafish [FHM data set]
Effects of bisphenol A (BPA) on ovarian transcript profiles as well as targeted endpoints with endocrine/reproductive relevance were examined in two fish species, fathead minnow (Pimephales promelas) and zebrafish (Danio rerio), exposed in parallel using matched experimental designs. Four days of wa...
ORGANISM(S): Pimephales promelas 
2012-01-01 | E-GEOD-28353 | biostudies-arrayexpress
UnknownActive Transportation on a Complete Street: Perceived and Audited Walkability Correlates.
Not available
S-EPMC5615551 | biostudies-literature
TranscriptomicsWee1 Inhibition sensitizes prostate cancer cells to Hsp90 inhibitor to activate the intrinsic apoptotic pathway
Heat shock protein 90 (Hsp90) is an essential evolutionarily conserved molecular chaperone in eukaryotes. Cancer cells rely on Hsp90 to chaperone activated oncoproteins, and its involvement in numerous signaling pathways makes it an attractive target for drug development. Surprisingly, however, the ...
ORGANISM(S): Homo sapiens 
2013-01-10 | E-GEOD-38972 | biostudies-arrayexpress
TranscriptomicsDifferential regulation of microRNAs in skeletal muscle from monozygotic twins discordant for type 2 diabetes
Analysis of microRNA expression in vastus lateralis muscle biopsies from 11 genetically identical twin pairs discordant for type 2 diabetes. This eliminates the influence of genotype and leads to the identification of microRNAs that are exclusively influenced by environmental (non-genetic) factors. ...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-38835 | biostudies-arrayexpress
TranscriptomicsTemporal development of necrotizing enterocolitis in the preterm pig
Necrotizing enterocolitis (NEC), a serious gastrointestinal disease that afflicts 5-10% of preterm infants, often progresses rapidly from mild food intolerance into extensive haemorrhage, inflammation and necrosis. Events leading to NEC have remained poorly defined. Similar disease characteristics a...
ORGANISM(S): Sus scrofa 
2010-05-07 | E-GEOD-13516 | biostudies-arrayexpress
UnknownBrentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin's Lymphoma.
Not available
S-EPMC5819601 | biostudies-literature
TranscriptomicsAmniotic fluid and necrotizing enterocolitis in preterm pigs
Preterm neonates are susceptible to gastrointestinal (GI) disorders such as necrotizing enterocolitis (NEC). Maternal milk, and especially colostrum, protects against NEC via growth promoting, immunomodulatory and antimicrobial factors. The fetal enteral diet, amniotic fluid (AF), contains similar b...
ORGANISM(S): Sus scrofa 
2010-05-06 | E-GEOD-13515 | biostudies-arrayexpress
UnknownAcetylsalicylic acid suppression of the PI3K pathway as a novel medical therapy for head and neck lymphatic malformations.
Not available
S-EPMC9632366 | biostudies-literature
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