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UnknownMitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription.
Not available
S-EPMC6128689 | biostudies-literature
UnknownMio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes
Not available
S-JCBD-201410001 | bioimages
ProteomicsStructural Basis for CAL1-Mediated Centromere Maintenance
Intermolecular interactions stabilising the CAL1–CENP-A/H4 complex were analysed using chemical Cross-Linking Mass Spectrometry (CLMS). Purified recombinant CAL11-160–CENP-A101-225–H4 complex was crosslinked using EDC and BS3. The crosslinked peptides were analysed by mass spectrometry to identify i...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-03-11 | PXD017238 | Pride
Cal1/cenp-a/cenp-c/centromeres/chromosome segregation 
ProteomicsStructural basis for the assembly of Mis18a/b core modules
The centromere, defined by the enrichment of CENP-A (a Histone H3 variant) containing nucleosomes, is a specialised chromosomal locus that acts as a microtubule attachment site. To preserve centromere identity, CENP-A levels must be maintained through active CENP-A loading during the cell cycle. A c...
ORGANISM(S): Homo sapiens (Human) 
2024-05-15 | PXD047345 | Pride
Cenp-a Mis18 complex Centromere 
UnknownHuman papillomavirus in retinoblastoma: A tertiary eye care center study from South India.
Not available
S-EPMC8482879 | biostudies-literature
UnknownAurora B controls kinetochore–microtubule attachments by inhibiting Ska complex–KMN network interaction
Not available
S-JCBD-201109001 | bioimages
ProteomicsA systematic analysis of Trypanosoma brucei chromatin factors identifies novel protein interaction networks associated with sites of transcription initiation and termination
Nucleosomes composed of histones are the fundamental units around which DNA is wrapped to form chromatin. Transcriptionally active euchromatin or repressive heterochromatin is regulated in part by the addition or removal of histone post-translational modifications (PTMs) by ‘writer’ and ‘eraser’ enz...
ORGANISM(S): Trypanosoma brucei 
2021-08-05 | PXD026743 | Pride
Proteomics Trypanosoma brucei Chromatin 
UnknownEpigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance.
Not available
S-EPMC5114538 | biostudies-literature
UnknownBelonolaimus longicaudatus: An Emerging Pathogen of Peanut in Florida.
Not available
S-EPMC4492293 | biostudies-literature
UnknownMio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes.
Not available
S-EPMC4494011 | biostudies-literature
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