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UnknownImpatiensyingjingensis (Balsaminaceae), a new species from Sichuan, China.
Not available
S-EPMC11176816 | biostudies-literature
MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
ProteomicsIn vivo fitness of sul gene-dependent sulfonamide-resistant Escherichia coli in the mammalian gut
Sulfonamides are traditional synthetic antimicrobial agents used in clinical and veterinary medical settings. Their long-term excessive overuse has resulted in widespread microbial resistance, limiting their application for medical interventions. Resistance to sulfonamides is primarily conferred by ...
ORGANISM(S): Escherichia Coli Str. K-12 Substr. Mg1655 
2024-07-04 | PXD053633 |
ProteomicsAddressing Enzymatic-Independent Tumor-Promoting Function of NAMPT via PROTAC-Mediated Degradation
The rate-limiting enzyme of salvage pathway for NAD+ synthesis, NAMPT, is aberrantly overexpressed in a variety of tumor cells and is a poor prognosis factor for patient survival. NAMPT plays a major role in tumor cell proliferation, acting concurrently as a NAD+ synthase and unexpectedly, an extrac...
ORGANISM(S): Homo Sapiens 
2021-09-13 | PXD028453 |
ProteomicsAddressing Enzymatic-Independent Tumor-Promoting Function of NAMPT via two PROTAC-Mediated Degradation
The rate-limiting enzyme of salvage pathway for NAD+ synthesis, NAMPT, is aberrantly overexpressed in a variety of tumor cells and is a poor prognosis factor for patient survival. NAMPT plays a major role in tumor cell proliferation, acting concurrently as an NAD+ synthase and unexpectedly, an extra...
ORGANISM(S): Homo Sapiens 
2022-01-24 | PXD031185 |
ProteomicsThe LC-MS/MS data of EVs derived from Talaromyces marneffei
Our experiment showed that the immunostimulatory effect of EVs derived from Talaromyces marneffei(TM) was significantly weaken with protease pretreatment, but not in pretreatment with dsDNA and RNase A hydrolase. To further investigate its protein composition, EVs derived from TM were further analyz...
ORGANISM(S): Talaromyces Marneffei 
2020-10-26 | PXD022162 |
UnknownEfficacy, safety and immunogenicity of a recombinant human papillomavirus bivalent (types 16, 18) vaccine in healthy 18-30-year-old Chinese women: a phase III, double-blind, randomized, controlled trial.
Not available
S-EPMC12870096 | biostudies-literature
ProteomicsDissection of Blood Ecosystem in SARS-CoV-2 Omicron Patients
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD045174 |
TranscriptomicsYAP Inhibition in HCC cells (Hep3B)
siRNA-mediated inhibition compared to untreated cells and cells transfected with nonsense siRNA. Loss of contact inhibition and anchorage-independent growth are hallmarks of cancer cells. In this context, frequent inactivation of the Hippo pathway and subsequent nuclear enrichment of the transcripti...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-GEOD-35004 | biostudies-arrayexpress
UnknownThe influence of coronavirus disease 2019 on emergency department visits in Nanjing, China: A multicentre cross-sectional study.
Not available
S-EPMC7415345 | biostudies-literature
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