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GenomicsPUMCH-ICT Hepatocellular Carcinoma Study Data Access Committee
Data Access Committee EGAC00001000627
EGAC00001000627 | EGA
GenomicsPUMCH-ICT Hepatocellular Carcinoma Study Data Access Committee
Data Access Committee EGAC00001000070
EGAC00001000070 | EGA
ProteomicsDiscovering new peripheral plasma biomarkers to identify cognitive decline in type 2 diabetes
Type 2 diabetes mellitus (T2DM) is an independent risk factor of Alzheimer's disease (AD), thus, identifying who among the increasing T2DM populations may develop into AD is important for early intervention. By using TMT-labeling coupled high-throughput mass spectrometry, we conducted a comprehensiv...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD027870 | Pride
Type 2 diabetes Mild cognitive impairment Proteomics Cip2a Alzheimer's disease Diagnostic biomarkers 
ProteomicsTau accumulation induces spatial memory deficit via disrupting medial septum-hippocampus cholinergic pathway
By precisely dissected MS for proteomics, we found that donepezil remarkably restored (at high dose), even elevated (at low dose) the level of vacuolar protein sorting-associated protein 37D (VP37D), an autophagy-related protein, in hTauMS mice.
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD023297 | Pride
Mouse Medial septum Hippocampus Alzheimer’s disease Cholinergic neuron Tau accumulation 
ProteomicsPlatelet biomarkers identifying mild cognitive impairment in type 2 diabetes patients
Here, we performed platelet proteomics in T2DM patients with MCI (T2DM-MCI) and without MCI (T2DM-nMCI)
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD023316 | Pride
Alzheimer's disease  mild cognitive impairment  type 2 diabetes mellitus  peripheral biomarkers  platelet  proteomics  optineurin 
Genomicsena-DATASET-CAS_CN-25-05-2017-05:37:34:660-591 - samples
The differentiation of distinct multifocal hepatocellular carcinoma (HCC): multicentric disease vs. intrahepatic metastases, in which the management and prognosis varies substantively, remains problematic. We aim to stratify multifocal HCC and identify novel diagnostic and prognostic biomarkers by p...
EGAD00001003348 | EGA
Genomicsena-DATASET-CAS_CN-17-03-2017-16:16:33:917-247 - samples
Poly A transcriptome sequence of mutifocal hepatocelular carcinoma
EGAD00001003231 | EGA
Genomicswhole genome sequence data of multifocal hepatocellular carcinoma
Background & Aims: The differentiation of distinct multifocal hepatocellular carcinoma (HCC): multicentric disease vs. intrahepatic metastases, in which the management and prognosis varies substantively, remains problematic. We aim to stratify multifocal HCC and identify novel diagnostic and prognos...
EGAS00001002338 | EGA
GenomicsPoly(A) RNA sequencing of hepatocellular carcinoma tumors and their matched noncancerous liver tissues
Background & Aims: The differentiation of distinct multifocal hepatocellular carcinoma (HCC): multicentric disease vs. intrahepatic metastases, in which the management and prognosis varies substantively, remains problematic. We aim to stratify multifocal HCC and identify novel diagnostic and prognos...
EGAS00001002337 | EGA
ProteomicsTargeting mitochondria-inflammation circuit by β-hydroxybutyrate mitigates heart failure with preserved ejection fraction
Rationale: Over 50% of heart failure patients have preserved, rather than reduced ejection fraction (HFpEF vs. HFrEF). Complexity of its pathophysiology and the lack of animal models hamper the development of effective therapy for HFpEF. Objective: This study was designed to investigate the metabol...
ORGANISM(S): Mus Musculus 
2021-10-22 | PXD021957 |
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