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ProteomicsThe mass spectrometry-based proteomics analysis of macrophages
Defective autophagy is linked to proinflammatory diseases. However, the mechanisms by which autophagy limits inflammation remain elusive. Here, we found that the pan-FGFR inhibitor LY2874455 efficiently activated autophagy and suppressed innate inflammation in macrophages stimulated by lipopolysacch...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD038747 | Pride
Macrophage  lps  immunoproteasome 
ProteomicsGlobal quantitative analysis of proteomic of mice with liver fibrosis based on DIA and PRM technology
Liver fibrosis (LF) is a kind of progressive liver injury reaction. The goal of this study was to achieve a more detailed understanding of the molecular changes in response to CCl4-induced LF through the identification of a differentially expressed liver proteomic. A total of 302 differentially expr...
ORGANISM(S): Mus Musculus 
2023-03-14 | PXD040876 |
ProteomicsS-nitrosocysteine proteomics of Schistosoma japonicum collected from infected mice and rats
Rats and mice were infected with Schistosoma japonicum, and the worms were collected from infected rats and mice. Worms in rats were exposed to high level of NO, while the worms in mice were not. Then a S-nitrosocysteine proteomics of Schistosoma japonicum collected from infected rats and mice was p...
ORGANISM(S): Schistosoma Japonicum 
2024-04-19 | PXD041667 |
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