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UnknownLack of association between apolipoprotein C3 gene polymorphisms and risk of nonalcoholic fatty liver disease in a Chinese Han population.
Not available
S-EPMC3974535 | biostudies-literature
UnknownPNPLA3 I148M variant in nonalcoholic fatty liver disease: demographic and ethnic characteristics and the role of the variant in nonalcoholic fatty liver fibrosis.
Not available
S-EPMC4299331 | biostudies-literature
UnknownAromatase deficiency in a Chinese adult man caused by novel compound heterozygous CYP19A1 mutations: effects of estrogen replacement therapy on the bone, lipid, liver and glucose metabolism.
Not available
S-EPMC4457386 | biostudies-literature
UnknownTransplantation of a beating heart: A first in man.
Not available
S-EPMC9019404 | biostudies-literature
GenomicsGenome-wide chromatin maps of T-cell acute lymphoblastic leukemia (T-ALL) [ChIP-seq]
Here we modeled T-ALL resistance to Notch inhibition, identifying M-bM-^@M-^XpersisterM-bM-^@M-^Y cells that readily expand in the presence of gamma secretase inhibitor (GSI) and the absence of Notch signaling. Rare persister cells are already present in naM-CM-/ve T-ALL populations, and the reversi...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-GEOD-54379 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human neural stem cells treated with vehicle (EtOH, 0.01%) and tert-butylhydroquinone (tBHQ, 20A?M) for 24h and assayed with long oligonucleotide arrays verse short oligonucleotide arrays-CTX066
Both in situ synthesized long oligo arrays from Agilent Technologies and short oligo arrays from Affymetrix were used to meausre differential gene expression in RNA samples generated from human neural stem cells treated with vehicle (EtOH, 0.01%) and tert-butylhydroquinone (tBHQ, 20µM) for 24h. For...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-759 | biostudies-arrayexpress
TranscriptomicsExpression Data from HNF4a RNAi Knockdown in HepG2 cells
HNF4a is an important liver transcription factor that regulates at least a thousand genes in the liver. Here we used expression profiling in HepG2 cells, a hepatocellular carcinoma cell line, in which HNF4a was knocked down by RNAi to identify some of those target genes. This dataset accompanies the...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-29084 | biostudies-arrayexpress
TranscriptomicsMechanisms for U2AF to define 3M-bM-^@M-2 splice sites and regulate alternative splicing in the human genome
The U2AF heterodimer has been well studied for its role in defining functional 3M-bM-^@M-^Y splice sites in pre-mRNA splicing, but many fundamental questions still remain unaddressed regarding the function of U2AF in mammalian genomes. Through genome-wide analysis of U2AF-RNA interactions, we report...
ORGANISM(S): Homo sapiens 
2014-10-08 | E-GEOD-61603 | biostudies-arrayexpress
TranscriptomicsExpression profiling of primary glioma samples
Background: Signaling by receptor tyrosine kinases (RTK) is frequently dysregulated in gliomas. Inter-individual variability in the causes for dysregulated RTK signaling may have hampered the efficacy of targeted therapies. Using gene expression modules around key regulators in the RAS-RAF-MEK-MAPK ...
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-74462 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human neural stem and neuroblastoma cells
Both in situ synthesized long oligo arrays from Agilent Technologies and short oligo arrays from Affymetrix were used to meausre differential gene expression in RNA samples generated from (1) human neural stem cells treated with vehicle (EtOH, 0.01%) and tert-butylhydroquinone (tBHQ, 20µM) for 24h,...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-768 | biostudies-arrayexpress
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