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TranscriptomicsTranscriptome sequencing of Pteropus alecto and Myotis davidii
Deep sequencing of mRNA from Pteropus alecto and Myotis davidii Analysis of ploy(A)+ RNA of Pteropus alecto and Myotis davidii
ORGANISM(S): Pteropus alecto 
2012-12-18 | E-GEOD-39933 | biostudies-arrayexpress
ProteomicsThe function of sirtuin family in NER
The role of sirtuin family in regulating DNA DSB repair has been extensively investigated, and here, we explore the molecular mechanisms of Sirtuin family in nucleotide excision repair.
ORGANISM(S): Homo Sapiens 
2020-08-04 | PXD020721 |
ProteomicsLiP-small molecule mapping of Farrerol
Limited proteolysis combined with mass spectrometry of farrerol treated. Briefly, cell lysates containing approximately 500 μg of total protein sample were incubated with farrerol or vehicle (DMSO) for 10 min at 25 °C. Proteinase K (5 μg, Sigma–Aldrich) was added simultaneously to each sample for t...
ORGANISM(S): Homo Sapiens 
2022-08-25 | PXD036308 |
ProteomicsProteome analysis of outer membrane vesicles from a highly virulent strain of Haemophilus parasuis
In this study, we investigated the secretion of OMVs from a clinical H. parasuis isolate strain (H45). In addition, we further analyzed the characterization, the comprehensive proteome and the virulence potential of OMVs. Our data demonstrated that H. parasuis could secrete OMVs into the extracellul...
ORGANISM(S): Glaesserella Parasuis 
2021-11-01 | PXD029451 |
ProteomicsCeramide Disrupts TM9SF2-PGK1 Axis to Redirect PD-L1 Trafficking and Enhance Antitumor Immunity
The programmed cell death protein 1 (PD-1) / programmed death-ligand 1 (PD-L1) axis represents a cornerstone of cancer immunotherapy, yet the dynamic shuttling of PD-L1 between endosomal recycling and lysosomal degradation routes limits durable responses. Using a CRISPR screen targeting glycosphingo...
ORGANISM(S): Homo Sapiens 
2026-02-27 | PXD075012 |
ProteomicsMouse Testis IP-MS Analysis of TEX44 Interacting Proteins
Through whole-exome sequencing of 800 patients with asthenozoospermia, we identified biallelic TEX44 variants in six individuals, all of whom exhibited defective mitochondrial sheath assembly and impaired sperm motility. Using Tex44 knockout mice, we demonstrated that TEX44 interacts with carnitine ...
ORGANISM(S): Mus Musculus 
2025-02-20 | PXD060989 |
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2020-07-30 | PXD020653 |
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