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ProteomicsProteomic analysis of human circulating neutrophils upon multi states
Neutrophils exhibited remarkable plasticity and heterogenicity in both homeostasis and pathology conditions. Here, we conducted a “multi-states” proteomics methodology to explore how neutrophils respond upon infection and inflammation stress including bacterial analog LPS, virus analog Poly(I:C), pr...
ORGANISM(S): Homo Sapiens 
2024-12-23 | PXD059138 |
ProteomicsProteome-wide Hyposuccinylation of Esophageal Squamous Cell Cancer to Promotion of Tumor Metabolism and Migration
We identify abnormal protein and post-translational modification (PTM) pathways, including significantly downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways inextricably linked with can...
ORGANISM(S): Homo Sapiens 
PXD021567 |
ProteomicsHistone PTMs dataset for Hyposuccinylation Derived from Abnormal Metabolism Promotes the Cell Migration of Esophageal Squamous Cell Cancer
We identify abnormal protein and post-translational modification (PTM) pathways, including many downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways and the reduced succinyl-CoA may lead...
ORGANISM(S): Homo Sapiens 
PXD021700 |
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