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TranscriptomicsCaste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior
Eusocial insects have evolved the capacity to generate adults with distinct morphological, reproductive and behavioural phenotypes from the same genome. Recent studies suggest that RNA editing might enhance the diversity of gene products at the post-transcriptional level, particularly to induce func...
ORGANISM(S): Acromyrmex echinatior 
2014-10-02 | E-GEOD-51576 | biostudies-arrayexpress
ProteomicsLabel-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line
Hepatitis B virus (HBV) infection is a major health problem worldwide. Recent evidence suggests that various viruses can manipulate the infection process by secretion of specific viral and cellular components into exosomes, small nanometer-sized (30-150 nm) vesicles secreted from various cells. Howe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080718 | MassIVE
ProteomicsGlycosylation detection of carcinoembryonic antigen in human plasma
We develop a method with high sensitivity and reproducibility to comprehensively illustrated the glycosylation of plasma CEA based on trifunctional probe and multi-enzymatic approach. Site-specific glycoforms of plasma CEA differed in patients with different cancers and the progression of CRC.
ORGANISM(S): Homo Sapiens 
2023-10-31 | PXD046518 |
GenomicsGonadal DNA methylomes of half-smooth tongue sole Cynoglossus semilaevis
Environmental sex determination (ESD) occurs in divergent, phylogenetically unrelated taxa, and in some species co-occurs with genetic sex determination (GSD) mechanisms. Although epigenetic regulation in response to environmental effects has long been proposed to be associated with ESD, a systemic ...
ORGANISM(S): Cynoglossus semilaevis 
2014-01-23 | E-GEOD-41129 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression analysis in Down syndrome: dynamic variation and insight into immunodeficiency
Down syndrome (DS) is caused by triplication of Human chromosome 21 (Hsa21) and associated with an array of deleterious phenotypes, including mental retardation, heart defects and immunodeficiency. Spatio-temporal patterns of genome-wide expression are critical to the understanding of DS. We used a ...
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-35665 | biostudies-arrayexpress
ProteomicsPredictive Value of Proteomic Markers for Advanced Rectal Cancer with Neoadjuvant Chemoradiotherapy
Thirteen paired pre- and post-nCRT sera from rectal cancer patients were analyzed by isobaric tags for relative and absolute quantitation (iTRAQ) method. Twenty-five proteins were selected for validation by parallel reaction monitoring (PRM) in ninety-one patients.
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032117 |
ProteomicsProteomic and transcriptome analysis of DIA protein in Morchella edulis
In proteomics, DIA technology, as a high-throughput and high-sensitivity protein detection technique, can comprehensively and accurately identify and quantify proteins in samples. For morel mushrooms, DIA proteomic analysis can provide a deeper understanding of their protein composition, structure, ...
ORGANISM(S): Morchella Sextelata 
2024-11-25 | PXD058217 |
ProteomicsProteins raw data using CT-1 in MDA-MB-231
The MDA-MB-231 cells were treated with CT-1 for 24 h. Then the cells were collected for proteomic analysis. SDT buffer was used for sample lysis and protein extraction. Protein digestion by trypsin was performed according to filter-aided sample preparation (FASP) procedure described by Matthias Mann...
ORGANISM(S): Homo Sapiens 
2024-10-30 | PXD057337 |
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