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N4-acetylcytidine (ac4C), a conserved but recently rediscovered RNA modification on tRNAs, rRNAs and mRNAs, is catalyzed by N-acetyltransferase 10 (NAT10). Lysine acylation is a ubiquitous protein modification that controls protein functions. Our latest study demonstrates a NAT10-dependent ac4C modi...
ORGANISM(S): Homo Sapiens 
2024-04-26 | PXD049447 |
As innate immune cells, monocytes play a central role in antifungal immunity. Using proteome studies in primary human monocytes, which were stimulated by Candida albicans (yeast) in vitro. Here we describe the changes of proteins in monocytes and demonstrate that in the early stage of infection, th...
ORGANISM(S): Homo Sapiens 
2021-03-04 | PXD024515 |
Most of the carcinogenesis of colorectal cancer (CRC) follows the normal-adenoma-carcinoma (N-A-C) sequence. We aimed to identify the key proteins in the N-A-C sequence and describe the proteomic pattern of tubular adenoma, tubulovillous adenoma and high-grade neoplasia. This study used high-resolut...
ORGANISM(S): Homo Sapiens 
2021-01-30 | PXD023899 |
Two 75-cm2 flasks of ependymal cells derived from ten E18.5 Wdr47+/+ or Wdr47-/- embryos at the day 10 post serum starvation were harvested and motile cilia were purified for quantitative label-free proteomic analysis.
ORGANISM(S): Mus Musculus 
2021-09-07 | PXD028219 |
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