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ProteomicsA Novel High-Throughput Immunoaffinity LC-MS/MS Assay for P III-NP and other Fragments of Type III Procollagen in Human Serum
The amino-terminal propeptide of type III procollagen (P-III-NP) is used with IGF-I to detect the illicit use of growth hormone and to monitor growth hormone therapy. However, the only currently available assays for P-III-NP are immunoassays, which are not well harmonized. In addition, other fragmen...
ORGANISM(S): Homo Sapiens 
2024-10-28 | PXD052245 | panorama
TranscriptomicsIschemic vs. nephrotoxic acute renal failure, early time points (2h and 8h)
Acute renal failure (ARF) has high morbidity and mortality. In animal ARF models, effective treatments must be administered before or shortly after the insult, limiting their clinical potential. We used microarrays to identify early biomarkers that distinguish ischemic from nephrotoxic ARF, or tha...
ORGANISM(S): Rattus norvegicus 
2010-07-01 | E-GEOD-3219 | biostudies-arrayexpress
UnknownStatin-Associated Cardiomyopathy Responds to Statin Withdrawal and Administration of Coenzyme Q10.
Not available
S-EPMC6730959 | biostudies-literature
TranscriptomicsMutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
Mutations of the KRAS oncogene are predictive for resistance to treatment with antibodies against the epithelial growth factor receptor in patients with colorectal cancer. Overcoming this therapeutic dilemma could potentially be achieved by the introduction of drugs that inhibit signaling pathways t...
ORGANISM(S): Homo sapiens 
2011-03-11 | E-GEOD-20842 | biostudies-arrayexpress
GenomicsOMRF SLEGEN GWAS Data from European-American Women with Lupus

"Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with complex etiology but strong clustering in families (lambda(S) = approximately 30). We performed a genome-wide association scan using 317,501 SNPs in 720 women of European ancestry with SLE and in 2,337 controls,...

phs000202.v1.p1 | EGA
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
UnknownRoot Exudates Alter the Expression of Diverse Metabolic, Transport, Regulatory, and Stress Response Genes in Rhizosphere Pseudomonas.
Not available
S-EPMC8079746 | biostudies-literature
Unknown5-year survival in patients with relapsed or refractory chronic lymphocytic leukemia in a randomized, phase III trial of fludarabine plus cyclophosphamide with or without oblimersen.
Not available
S-EPMC5321078 | biostudies-literature
ProteomicsMALDI rat liver anticancer drug spiked-in dataset (imzML)
For the MALDI-MSI experiment, we selected 12 different drugs. The drugs were purchased from the LC Laboratories (Woburn, MA; CAS numbers: dabrafenib: 1195765-45-7, dasatinib: 302962-49-8, erlotinib: 183321-74-6, gefitinib: 184475-35-2, imatinib: 152459-95-5, lapatinib: 388082-78-8, pazopanib: 444731...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-11-06 | PXD016146 | Pride
Imzml ground truth spiked-in drugs 
GenomicsInternational Consortium on the Genetics of Systemic Lupus Erythematosus (SLEGEN)

The genetic makeup of an individual strongly influences the risk of developing systemic lupus erythematosus (SLE). The identification of genes that predispose an individual to SLE will lead to earlier and better diagnosis, better treatments, and possibly prevention.

To this end, t...

phs000216.v1.p1 | EGA
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